Land: Vereinigte Staaten
Sprache: Englisch
Quelle: NLM (National Library of Medicine)
PRADOFLOXACIN (UNII: 6O0T5E048I) (PRADOFLOXACIN - UNII:6O0T5E048I)
Elanco US Inc.
ORAL
PRESCRIPTION
DO NOT USE IN DOGS. Pradofloxacin has been shown to cause bone marrow suppression in dogs. Dogs may be particularly sensitive to this effect, potentially resulting in severe thrombocytopenia and neutropenia. Quinolone-class drugs have been shown to cause arthropathy in immature animals of most species tested, the dog being particularly sensitive to this side effect. Pradofloxacin is contraindicated in cats with a known hypersensitivity to quinolones.
Bottle Size 15 mL 30 mL Approved by FDA under NADA # 141-344 90209274_PA502558X Made in Germany © 2022 Elanco or its affiliates. Veraflox, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. Manufactured for: Elanco US Inc. Greenfield, IN 46140 U.S.A. Revised: May 2022 Elanco ™
New Animal Drug Application
VERAFLOX- PRADOFLOXACIN SUSPENSION ELANCO US INC. ---------- VERAFLOX™ _ELANCO_™ (pradofloxacin) ORAL SUSPENSION FOR CATS 25 MG/ML DO NOT USE IN DOGS. FEDERAL LAW PROHIBITS THE EXTRALABEL USE OF THIS DRUG IN FOOD-PRODUCING ANIMALS. CAUTION Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION Pradofloxacin is a fluoroquinolone antibiotic and belongs to the class of quinoline carboxylic acid derivatives. Its chemical name is: 7-[(4aS) octahydro-6H-pyrrolo [3, 4-b] pyridine-6yl]-8- cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinoline carboxylic acid. Each mL of VERAFLOX Oral Suspension provides 25 mg of pradofloxacin. INDICATION VERAFLOX is indicated for the treatment of skin infections (wounds and abscesses) in cats caused by susceptible strains of _Pasteurella multocida, Streptococcus canis,_ _Staphylococcus aureus, Staphylococcus felis,_ and _Staphylococcus pseudintermedius._ DOSAGE AND ADMINISTRATION Shake well before use. To ensure a correct dosage, body weight should be determined as accurately as possible. The dose of VERAFLOX is 7.5 mg/kg (3.4 mg/lb) body weight once daily for 7 consecutive days. Use the syringe provided to ensure accuracy of dosing to the nearest 0.1 mL. Rinse syringe between doses. A sample of the lesion should be obtained for culture and susceptibility testing prior to beginning antibacterial therapy. Once results become available, continue with appropriate therapy. If acceptable response to treatment is not observed, or if no improvement is seen within 3 to 4 days, then the diagnosis should be re-evaluated and appropriate alternative therapy considered. CONTRAINDICATIONS DO NOT USE IN DOGS. PRADOFLOXACIN HAS BEEN SHOWN TO CAUSE BONE MARROW SUPPRESSION IN DOGS. DOGS MAY BE PARTICULARLY SENSITIVE TO THIS EFFECT, POTENTIALLY RESULTING IN SEVERE THROMBOCYTOPENIA AND NEUTROPENIA. Quinolone-class drugs have been shown to cause arthropathy in immature animals of most species tested, the dog being particularly sensitive to this side effect. Lesen Sie das vollständige Dokument