Prozine 10 Syrup 10mg5ml

Land: Malaysia

Sprache: Englisch

Quelle: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Wirkstoff:

Promethazine HCl

Verfügbar ab:

SUNWARD PHARMACEUTICAL SDN. BHD.

INN (Internationale Bezeichnung):

Promethazine HCl

Einheiten im Paket:

1 L; 1 L; 60ml mL; 100ml mL; 120ml mL; 120ml mL; 60ml mL; 100ml mL

Hergestellt von:

SUNWARD PHARMACEUTICAL SDN. BHD.

Gebrauchsinformation

PROZINE SYRUP
Promethazine hydrochloride (5mg / 5ml, 10mg / 5ml)
1
_ CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET
1. What Prozine Syrup is used for
2. How Prozine Syrup works
3. Before you use Prozine Syrup
4. How to use Prozine Syrup
5. While you are using it
6. Side effects
7. Storage and disposal of Prozine Syrup
8. Product description
9. Manufacturer and Product Registration
Holder
10.Date of revision
WHAT PROZINE SYRUP IS USED FOR
Prozine Syrup is used as treatment for;

dermatographism (skin becoming raised red
lines after scratching).

rhinitis
(inflammation
of
the
mucous
membrane inside the nose).

nause and vomiting or as prevention with
certain type of anaesthesia, in surgery or
motion sickness.

mild, uncomplicated allergic skin manifes-
tations of hives and swelling of the deeper
layers of the skin.

as a sedative (to help people go to sleep and
control
their
anxiety)
before
and
after
surgery, and during labour.

improvement of allergic reactions to blood
or plasma.

allergic conjunctivitis (inflamation in eyes)
due to allergens and foods.
HOW PROZINE SYRUP WORKS
The active
ingredient
in the medicine is
promethazine
hydrochloride.
Promethazine
is
an
anti-histamine.
It
is
capable
of
producing sedative effects. It works by block-
ing a certain natural substance (histamine)
that
your
body
makes
during
an
allergic
reaction.
BEFORE YOU USE PROZINE SYRUP
_- When you must not use it _
Do not take this medicine if you:

are hypersensitive to promethazine, or any
of the other ingredients listed at the end of
the leaflet.
_ _

have
received
large
amounts
of
central
nerovous system (CNS) depressants (such
as
alcohol,
barbiturate,
opioid
pain
relievers).
_ _

have asthma.
_ _
_ _
_ _
_ _
_ _
_- Before you start to use it _
Tell your doctor before taking this medicine if
you have:

closed-angle glaucoma (increase pressure in
eyes).

stomach or duodenal ulcer.

enlargement of prostate or gastric outflow
obstruction.

bladder problems.

bone ma

Fachinformation

Each 5ml contains:
Promethazine HCl 10mg
PHARMACOLOGY:
Promethazine hydrochloride, a phenothiazine derivative, possesses
anti-histamine, sedative, anti-motion
sickness, anti-emetic and anti-cholinergic effects. The duration of
action is generally from four to six hours.
The major side reaction of this drug is sedation. As an anti-histamine
it acts by competitive antagonism, but
does not block the release of histamine. It antagonises in varying
degree most but not all of the
pharmacological effects of histamine.
It is readily absorbed from the gastro-intestinal tract. Following
oral administration the effects start within 15
to 20 minutes and are fully developed within one hour. The highest
concentration occurs in the lungs,
progressively lower concentration in the spleen, kidney, brain, muscle
and skin. Small amounts of the drug is
excreted unchanged, most appears as degradation products that are
almost completely excreted within 24
hours. The main site of metabolic transformation is the liver but the
lung and kidneys can also metabolise the
compound.
INDICATIONS:
In addition to its antihistaminic action, which is of marked potency
and prolonged duration, it also provides
antiemetic as well as sedative actions.
Promethazine HCl is useful in the management of the following
conditions:
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a
V
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b
c) Perennial and seasonal allergic rhinitis
g) Active and prophylactic treatment of motion sickness
d) Antiemetic therapy in postoperative patients
h) Allergic conjunctivitis due to inhalant allergens and foods
i ) Mild, uncomplicated allergic skin manifestation of urticaria and
angioedema
j ) Prevention and control of nausea and vomiting associated with
certain types of anaesthesia and surgery
k)
Sedation in both children and adults as well as relief of apprehension
and product