Land: Vereinigte Staaten
Sprache: Englisch
Quelle: NLM (National Library of Medicine)
TULATHROMYCIN (UNII: Q839I13422) (TULATHROMYCIN - UNII:Q839I13422)
Zoetis Inc.
TULATHROMYCIN
TULATHROMYCIN 100 mg in 1 mL
INTRAMUSCULAR
PRESCRIPTION
BRD – DRAXXIN Injectable Solution is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica , Pasteurella multocida , Histophilus somni , and Mycoplasma bovis ; and for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica , Pasteurella multocida , Histophilus somni , and Mycoplasma bovis . IBK – DRAXXIN Injectable Solution is indicated for the treatment of infectious bovine keratoconjunctivitis (IBK) associated with Moraxella bovis . Foot Rot – DRAXXIN Injectable Solution is indicated for the treatment of bovine foot rot (interdigital necrobacillosis) associated with Fusobacterium necrophorum and Porphyromonas levii . BRD – DRAXXIN Injectable Solution is indicated for the treatment of BRD associated with M. haemolytica, P. multocida, H. somni, and M. bovis. DRAXXIN Injectable Solution is indicated for the treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoni
DRAXXIN Injectable Solution is available in the following package sizes: 50 mL vial 100 mL vial 250 mL vial 500 mL vial
New Animal Drug Application
DRAXXIN- TULATHROMYCIN INJECTION, SOLUTION ZOETIS INC. ---------- DRAXXIN (TULATHROMYCIN INJECTION) INJECTABLE SOLUTION ANTIBIOTIC 100 mg of tulathromycin/mL For use in beef cattle (including suckling calves), non-lactating dairy cattle (including dairy calves), veal calves, and swine. Not for use in female dairy cattle 20 months of age or older. CAUTION Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION DRAXXIN Injectable Solution is a ready-to-use sterile parenteral preparation containing tulathromycin, a semi-synthetic macrolide antibiotic of the subclass triamilide. Each mL of DRAXXIN contains 100 mg of tulathromycin as the free base in a 50% propylene glycol vehicle, monothioglycerol (5 mg/mL), with citric and hydrochloric acids added to adjust pH. DRAXXIN consists of an equilibrated mixture of two isomeric forms of tulathromycin in a 9:1 ratio. Structures of the isomers are shown below. Figure 1. ® The chemical names of the isomers are (2R,3S, 4R,5R,8R,10R,11R,12S,13S,14R)-13- [[2,6-dideoxy-3-C-methyl-3-Ο-methyl-4-C-[(propylamino) methyl]-α-L-ribo-hexopyrano- syl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3- (dimethylamino)-β-D-xylohexopyranosyl]-oxy]-1-oxa-6-azacyclopentadecan-15-one and (2R, 3R,6R, 8R,9R,10S,11S,12R)-11-[[2,6-dideoxy-3-C-methyl- 3-Ο-methyl-4-C- [(propylamino)methyl]-α-L-ribo-hexopyrano-syl]oxy]-2-[(1R,2R)-1,2-dihydroxy-1- methylbutyl]-8-hydroxy-3,6,8,10,12-pentamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)- β-D-xylohexopyranosyl]oxy]-1-oxa-4-azacyclotridecan-13-one, respectively. INDICATIONS BEEF AND NON-LACTATING DAIRY CATTLE BRD – DRAXXIN Injectable Solution is indicated for the treatment of bovine respiratory disease (BRD) associated with _Mannheimia haemolytica_, _Pasteurella_ _multocida_, _Histophilus somni_, and _Mycoplasma bovis_; and for the control of respiratory disease in cattle at high risk of developing BRD associated with _Mannheimia_ _haemolytica_, _Pasteurella multocida_, _Histoph Lesen Sie das vollständige Dokument