CLOMICALM TABLET

Land: Kanada

Sprache: Englisch

Quelle: Health Canada

Wirkstoff:

CLOMIPRAMINE HYDROCHLORIDE

Verfügbar ab:

VIRBAC AH, INC.

Dosierung:

5MG

Darreichungsform:

TABLET

Zusammensetzung:

CLOMIPRAMINE HYDROCHLORIDE 5MG

Verabreichungsweg:

ORAL

Einheiten im Paket:

15G/50G

Verschreibungstyp:

Prescription

Therapiegruppe:

DOGS

Produktbesonderheiten:

Active ingredient group (AIG) number: 0109212006

Berechtigungsstatus:

APPROVED

Berechtigungsdatum:

1998-12-11

Gebrauchsinformation

_302308-03_
DIN 02239207
DIN 02239206
DIN 02239205
®
_CLOMIPRAMINE HYDROCHLORIDE TABLETS _
_Comprimés de chlorhydrate de clomipramine_
PR
CLOMICALM
® 5 MG, 20 MG, 80 MG
Clomipramine Hydrochloride Tablets
CLOMICALM
®
(clomipramine hydrochloride) tablets are a twice
daily oral treatment for dogs which has been shown to be effective
when administered in combination with behaviour modification
techniques for the treatment of anxieties and stereotypies
(obsessive compulsive disorder).
INTRODUCTION
Virbac encourages you to take time to read this package
insert which describes the use of CLOMICALM (clomipramine
hydrochloride) to treat certain behavioural concerns in dogs.
CLOMICALM tablets are only available through veterinarians.
DESCRIPTION
Brownish-grey, divisible tablet, scored on both sides. The active
ingredient in CLOMICALM tablets are clomipramine hydrochloride.
The active ingredient in vivo is clomipramine and its major
metabolite, desmethylclomipramine. Both clomipramine and
desmethylclomipramine contribute to the broad-spectrum of
action of CLOMICALM tablets by blocking the neuronal re-uptake
of both noradrenaline and serotonin (5-HT). CLOMICALM tablets
therefore possess the properties of both a tricyclic antidepressant
and a serotonin re-uptake inhibitor.
INDICATIONS
Treatment of anxieties. Treatment of stereotypies (obsessive
compulsive disorders) such as lick dermatitis.
DOSAGE
CLOMICALM tablets are administered twice daily at a dose of
1-2 mg/kg to give a total daily dose of 2-4 mg/kg according to the
following table:
DOSAGE PER ADMINISTRATION
BODY
WEIGHT
CLOMICALM
5
MG
CLOMICALM
20
MG
CLOMICALM
80
MG
1.25 - 2.5
kg
½
tablet
---
---
>2.5 - 5
kg
1
tablet
---
---
>5 - 10
kg
---
½
tablet
---
>10 - 20
kg
---
1
tablet
---
>20 - 40
kg
---
---
½
tablet
>40 - 80
kg
---
---
1
tablet
ADMINISTRATION
CLOMICALM tablets are given orally with or without food. In
clinical trials, CLOMICALM tablets have been shown to be effective
when administered for 2-3 months in combination with behaviour
modification techniques