CIPROFLOXACIN tablet

Land: Vereinigte Staaten

Sprache: Englisch

Quelle: NLM (National Library of Medicine)

Wirkstoff:

CIPROFLOXACIN HYDROCHLORIDE (UNII: 4BA73M5E37) (CIPROFLOXACIN - UNII:5E8K9I0O4U)

Verfügbar ab:

Clinical Solutions Wholesale

INN (Internationale Bezeichnung):

CIPROFLOXACIN HYDROCHLORIDE

Zusammensetzung:

CIPROFLOXACIN 250 mg

Verschreibungstyp:

PRESCRIPTION DRUG

Berechtigungsstatus:

Abbreviated New Drug Application

Fachinformation

CIPROFLOXACIN- CIPROFLOXACIN TABLET
CLINICAL SOLUTIONS WHOLESALE
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CIPROFLOXACIN TABLETS 250 MG
WARNING:
Fluoroquinolones, including CIPROFLOXACIN TABLETS USP, 250 mg, 500 mg
and 750 mg,
are
associated with an increased risk of tendinitis and tendon rupture in
all ages. This risk is further
increased in older patients usually over 60 years of age, in patients
taking corticosteroid drugs,
and
in patients with kidney, heart or lung transplants (See WARNINGS).
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of Ciprofloxacin
Tablets USP, 250 mg, 500 mg and 750 mg and other antibacterial drugs
Ciprofloxacin Tablets USP, 250
mg, 500 mg and 750 mg should be used only to treat or prevent
infections that are proven or strongly
suspected to be caused by bacteria.
DESCRIPTION
Ciprofloxacin Hydrochloride Tablets USP, 250 mg, 500 mg and 750 mg are
synthetic broad spectrum
antimicrobial agents for oral administration. Ciprofloxacin
hydrochloride, USP, a fluoroquinolone, is
the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1,
4-dihydro-4-oxo-7-(1-
piperazinyl)-3-quinolinecarboxylic acid. It is a faintly yellowish to
light yellow crystalline substance
with a molecular weight of 385.8. Its empirical formula is C
H
FN
O
•HCl•H
O and its chemical
structure is as follows:
Ciprofloxacin is
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic
acid. Its empirical formula is C17H18FN3O3 and its molecular weight is
331.4. It is a faintly yellowish
to light yellow crystalline substance and its chemical structure is as
follows:
17
18
3
3
2
Ciprofloxacin Tablets USP are film-coated tablets and are available in
250 mg, 500 mg and 750 mg
(ciprofloxacin equivalent) strengths. Ciprofloxacin Tablets are white
to slightly yellowish. The
inactive ingredients are pregelatinized starch, microcrystalline
cellulose, colloidal silicon dioxide,
crospovidone, magnesium stearate, hypromellose, titanium dioxide,
polyethylene glycol and purified
water.
CLINICAL PHARM