CEFPODERM- cefpodoxime proxetil tablet

Land: Vereinigte Staaten

Sprache: Englisch

Quelle: NLM (National Library of Medicine)

Wirkstoff:

Cefpodoxime proxetil (UNII: 2TB00A1Z7N) (CEFPODOXIME - UNII:7R4F94TVGY)

Verfügbar ab:

Dechra Veterinary Products LLC

Verabreichungsweg:

ORAL

Verschreibungstyp:

PRESCRIPTION

Anwendungsgebiete:

INDICATION: Cefpoderm is indicated for the treatment of skin infections (wounds and abscesses) in dogs caused by susceptible strains of Staphylococcus pseudintermedius , Staphylococcus aureus , Streptococcus canis (group G, ß hemolytic), Escherichia coli , Pasteurella multocida , and Proteus mirabilis . CONTRAINDICATIONS: Cefpodoxime proxetil is contraindicated in dogs with known allergy to cefpodoxime or to the ß-lactam (penicillins and cephalosporins) group of antibiotics.

Produktbesonderheiten:

HOW SUPPLIED: Cefpoderm (cefpodoxime proxetil tablets) is available in the following strengths (cefpodoxime equivalent), colors, and sizes: 100 mg (yellow, scored, elliptical, debossed with PV on one side, 17 on the other side) Bottles of 100 NDC 17033-431-10 200 mg (orange, oblong, debossed with PV on one side, 18 on the other side) Bottles of 100 NDC 17033-432-10

Berechtigungsstatus:

Abbreviated New Animal Drug Application

Fachinformation

CEFPODERM- CEFPODOXIME PROXETIL TABLET
DECHRA VETERINARY PRODUCTS LLC
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CEFPODERM
(CEFPODOXIME PROXETIL TABLETS)
_For Oral Use in Dogs Only_
CAUTION: Federal (USA) law restricts this drug to use by or on the
order of a licensed
veterinarian.
DESCRIPTION:
Cefpodoxime proxetil is an orally administered, extended spectrum,
semi-synthetic
cephalosporin antibiotic. The chemical name is:
(+/-)-1-Hydroxyethyl(+)-(6R,7R)-7-[2-(2-
amino-4-thiazolyl)glyoxylamido]-3-methoxymethyl)-8-oxo-5-thia-1-azabicyclo
[4.2.0]oct-
2-ene-2-carboxylate, 7 -(Z)-(O-methyloxime), isopropyl carbonate
(ester) [87239-81-4].
CEFPODOXIME PROXETIL CHEMICAL STRUCTURE:
Cefpodoxime proxetil is a prodrug; its active metabolite is
cefpodoxime. All doses of
Cefpoderm (cefpodoxime proxetil tablets) are expressed in terms of the
active
cefpodoxime moiety. Cefpoderm is available as:
100 MG TABLET, each yellow, elliptical, scored tablet contains
cefpodoxime proxetil
equivalent to 100 mg of cefpodoxime.
200 MG TABLET, each orange, oblong, tablet contains cefpodoxime
proxetil equivalent
to 200 mg of cefpodoxime.
INDICATION:
Cefpoderm is indicated for the treatment of skin infections (wounds
and abscesses) in
dogs caused by susceptible strains of _Staphylococcus
pseudintermedius_,
_Staphylococcus aureus_, _Streptococcus canis _(group G, ß
hemolytic), _Escherichia coli_,
_Pasteurella multocida_, and _Proteus mirabilis_.
DOSAGE AND ADMINISTRATION:
DOSE RANGE: The dose range of Cefpoderm is 5-10 mg/kg (2.3-4.5 mg/lb)
body weight,
administered orally, once a day.
The dose may be given with or without food. The determination of
dosage for any
®
2
particular patient must take into consideration such factors as the
severity and nature
of the infection, the susceptibility of the causative organisms, and
the integrity of the
patient's host-defense mechanisms. Obtain a sample of the pathogenic
organism for
culture and sensitivity testing prior to beginning antimicrobial
therapy. Once results
become available, continue with appropriate therapy.
DURATION: Cefpo