Calcitriol-GA

Land: Australien

Sprache: Englisch

Quelle: Department of Health (Therapeutic Goods Administration)

Wirkstoff:

Calcitriol

Verfügbar ab:

Actavis Pty Ltd

Klasse:

Medicine Registered

Gebrauchsinformation

091215 Calcitriol-GA CMI v1 

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CALCITRIOL-GA 
_calcitriol 0.25 µg capsules _
_ _
_ _
CONSUMER  MEDICINE INFORMATION  

WHAT IS IN THIS LEAFLET 
This leaflet answers some common questions about 
Calcitriol-GA capsules.  
It does not contain all the available information.  
It does not take the place of talking to your doctor or 
pharmacist.  
All medicines have risks and benefits.  Your doctor has 
weighed the risks of you taking Calcitriol-GA capsules 
against the benefits they expect it will have for you.  
IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS 
MEDICINE, ASK YOUR DOCTOR OR PHARMACIST.  
KEEP THIS LEAFLET WITH THE MEDICINE.  You may need to 
read it again.  

WHAT CALCITRIOL-GA IS USED FOR 
Calcitriol-GA contains the active ingredient calcitriol, 
one of the naturally occurring and biologically active 
forms of Vitamin D.  Calcitriol acts in the body in a 
similar manner to Vitamin D. 
Calcitriol-GA is used to treat people with osteoporosis, 
a disease where the bones of the body weaken, and in 
the prevention of osteoporosis in people taking oral 
corticosteroids.  
Calcitriol-GA capsules are also prescribed for patients 
who have low blood calcium levels due to 
osteodystrophy (a type of bone disease), 
hypoparathyroidism (a condition where the parathyroid 
glands have decreased function) and rickets.  
Calcitriol-GA increases calcium absorption in the 
intestine and stimulates healthy bone growth.  
There are many different types of medicines used to 
treat bone conditions.  Calcitriol-GA belongs to a 
group of medicines known as vitamin D compounds.  
Your doctor may have prescribed Calcitriol-GA for 
another purpose.  ASK YOUR DOCTOR IF YOU HAVE ANY 
QUESTIONS WHY CALCITRIOL-GA HAS BEEN PRESCRIBED 
FOR YOU.  
This medicine is available only with a doctor's 
prescription.  
Calcitriol-GA is not addictive.  

BEFORE

Fachinformation

                Calcitriol-GA Product Information 
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CALCITRIOL-GA 
_ _
_PRODUCT INFORMATION _

_NAME OF THE MEDICINE: _

Calcitriol-GA 

GENERIC NAME: 

Calcitriol 

COMPOSITION:  

CAS 32222-06-3 

The chemical name for calcitriol is
(5_Z_,7_E_)-9,10-secocholesta-5,7,10(19)-triene-1α,3β,25-triol 
(calcitriol), the molecular formula is C
27
H
44
O
3
.  Calcitriol has a molecular weight of 416.65.  

DESCRIPTION:  

Calcitriol is a white, crystalline compound, which occurs naturally
in humans.  It is soluble in organic 
solvents but practically insoluble in water.  

Calcitriol is available as soft gelatin capsules containing 0.25
micrograms of calcitriol.  Each capsule 
also contains butylated hydroxyanisole, butylated hydroxytoluene,
coconut oil - fractionated, gelatin, 
glycerol, sorbitol (70 percent, non-crystallising), iron oxide red
and iron oxide yellow. 

PHARMACOLOGY:  
_ _
_Pharmacodynamics: _
Calcitriol is the most important active metabolite of vitamin D
3
.  It is normally 
formed in the kidney from its precursor 25-hydroxycholecalciferol
(25-HCC).  Physiological daily 
production is normally 0.5 - 1.0 
μg and is somewhat higher during periods of increased bone 
synthesis (eg growth or pregnancy).  

The natural supply of vitamin D in humans depends mainly on exposure
to ultraviolet rays of the sun 
for conversion of 7-dehydrocholesterol in the skin to vitamin D
3 
(cholecalciferol).  Vitamin D
3 
must be 

                Calcitriol-GA Product Information 
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metabolically activated in the liver and the kidney before it is full