Land: Australien
Sprache: Englisch
Quelle: Department of Health (Therapeutic Goods Administration)
Moxifloxacin
Bayer Australia Ltd
Medicine Registered
120424 Avelox PI Page 1 of 22 PRODUCT INFORMATION AVELOX ® (MOXIFLOXACIN HYDROCHLORIDE, BAYER) NAME OF THE MEDICINE Moxifloxacin hydrochloride (CAS number: 186826-86-8). Its empirical formula is C 21 H 23 FN 3 O 4 * HCl and has a molecular weight of 437.9. Moxifloxacin, a fluoroquinolone, differs from other quinolones in that it has a methoxy function at the 8-position and an _S,S_ configurated diazabicyclononyl ring moiety at the 7-position. Its chemical name is 1-cyclopropyl-7-{(_S,S_)-2,8- diaza-bicyclo[4.3.0]non-8-yl}-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride. It is a pale yellow substance. The substance shows no melting point but it decomposes above 250°C. It is sparingly soluble in water and methanol, slightly soluble in HCl and ethanol, and practicably insoluble in acetone and toluene. It has the following chemical structure: DESCRIPTION Avelox (moxifloxacin hydrochloride) is a synthetic broad spectrum antibacterial agent and is available as Avelox tablets for oral administration, and as Avelox IV infusion solution for intravenous administration. Avelox tablets are available as a 400 mg film-coated tablet. Besides the active ingredient, Avelox tablets also contain the following excipients: microcrystalline cellulose, croscarmellose sodium, lactose, magnesi Lesen Sie das vollständige Dokument