Asmol uni-dose

Land: Australien

Sprache: Englisch

Quelle: Department of Health (Therapeutic Goods Administration)

Wirkstoff:

Salbutamol sulfate

Verfügbar ab:

Alphapharm Pty Ltd

Klasse:

Medicine Registered

Gebrauchsinformation

ASMOL UNI-DOSE

_contains the active ingredient salbutamol_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Asmol uni-dose.
It does not contain all of the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have benefits and
risks. Your doctor has weighed the
risks of you using Asmol uni-dose
against the benefits they expect it
will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
USING THIS MEDICINE, TALK TO YOUR
DOCTOR OR PHARMACIST.
Keep this leaflet with your medicine.
You may need to read it again.
WHAT ASMOL UNI-DOSE
IS USED FOR
Asmol uni-dose are plastic ampoules
which contain a medicine called
salbutamol, as a liquid. The liquid is
changed into a fine mist of droplets
by the nebuliser.
Asmol uni-dose is used for the
treatment of asthma, bronchitis and
other breathing problems.
In people who have difficulty
breathing during exercise, Asmol
uni-dose may also be used before
exercise to keep the air passages
open.
Your doctor may have prescribed
Asmol uni-dose for another purpose.
Ask your doctor if you have any
questions about why Asmol uni-dose
has been prescribed for you.
It belongs to a group of medicines
called bronchodilators or beta-2
agonists. When your chest is tight or
when you are wheezing, Asmol uni-
dose is inhaled into the lungs and
works rapidly to open up the air
passages in your lungs to help you
breathe more easily.
The medicine in Asmol uni-dose
gives fast relief from your chest
symptoms and is often called a
'reliever' medicine.
There is no evidence that Asmol uni-
dose is addictive.
BEFORE YOU USE ASMOL
UNI-DOSE
_WHEN YOU MUST NOT USE IT_
DO NOT USE ASMOL UNI-DOSE IF YOU
HAVE AN ALLERGY TO ANY MEDICINE
CONTAINING SALBUTAMOL.
Some of the symptoms of an allergic
reaction may include:
•
shortness of breath
•
wheezing or difficulty breathing
•
swelling of the face, lips, tongue
or other parts of the body
•
rash, itching or hives on the skin.
DO NOT USE THIS MEDICINE I

Fachinformation

ASMOL uni-dose

_Salbutamol (sulfate)_ 
PRODUCT INFORMATION 
NAME OF THE MEDICINE

The active ingredient of Asmol uni-dose is Salbutamol (as salbutamol sulfate). 
The chemical name for salbutamol sulfate is: 1-(4-hydroxy-3-hydroxymethylphenyl)-2-(t-butylamino)ethanol sulfate. 
Its structural formula is:  
CHOH.CH
2
.NHC(CH
3
)
3
HOH
2
C
HO
H
2
SO
4
2

Molecular formula: 

Molecular Weight: 

CAS Registry No.: 
(C
13
H
21
NO
3
)
2
H
2
SO
4 

288.4   

51022-70-9 
DESCRIPTION

Salbutamol sulfate is a white or almost white odourless powder. It is soluble in 4 parts of water, slightly soluble in 
95% alcohol, in chloroform and solvent ether. 
PHARMACOLOGY

Salbutamol  is  a  relatively  selective  β
2
-adrenoreceptor  stimulant.  It  is  more  specific  than  both  isoprenaline  and 
orciprenaline for adrenergic β
2
-receptors. 
After oral and parenteral administration, stimulation of the β -receptors in the body, both β
1
 and β
2
, occurs because: 
(a)  β
2
 selectivity is not absolute, and 
(b)  higher  concentrations  of  salbutamol  occur  in the regions of these receptors with these modes of 
administration.   
This  results  in  the  β
1
  effect  of  cardiac  stimulation,  though  not  so  much  as  with  isoprenaline,  and  β
2
  effects  of 
peripheral vasodilation and hypotension, skeletal muscle tremor and uterine muscle relaxation. 
Metabolic effects such as hyperinsulinaemia and hyperglycaemia also may occur, although it is not known whether 
these effects are mediated by β
1
- or β
2
-receptors.  The serum potassium levels have a
tendency to fall. 
PHARMACOKINETICS 
Following inhalation, salbutamol acts topically on bronchial smooth muscle and initially the drug is undetectable in 
the blood.  After 2 to 3 h