Land: Malaysia
Sprog: engelsk
Kilde: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
PROMETHAZINE HYDROCHLORIDE
Duopharma Marketing Sdn. Bhd.
PROMETHAZINE HYDROCHLORIDE
1000 mcg/mL; 100Tablet Tablets; 100 Tablet Tablets
DUOPHARMA MANUFACTURING (BANGI) SDN BHD
1 _CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ PROEZINE FILM COATED TABLET Promethazine hydrochloride (25mg) WHAT IS IN THE LEAFLET 1. What Proezine Tablet is used for 2. How Proezine Tablet works 3. Before you use Proezine Tablet 4. How to use Proezine Tablet 5. While you are using it 6. Side effects 7. Storage and disposal of Proezine Tablet 8. Product description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT PROEZINE TABLET IS USED FOR Proezine Tablet may be provided to you for use in the following situations: • To treat allergic conditions of the upper respiratory tract and skin such as to relief symptoms of perennial (throughout the year) and seasonal rhinitis (inflammation of the mucous membrane inside the nose), hives. • To treat or stop you feeling sick or vomiting such as travel sickness or vomiting due to medicine or after operation. • To help you feel more relaxed before and after surgery and during labour. • For short term use: - To treat adults with difficulty sleeping - As a sedative (calm or inducing sleep) for children HOW PROEZINE TABLET WORKS This medicine contains the active ingredient Promethazine which is an antihistamine. Histamine is a chemical released into the body during an allergic reaction. It works by blocking the effects of histamine, calming down the body's allergic reaction and starting to relieve the symptoms. It also works directly on the brain to help you feel more relaxed. BEFORE YOU USE PROEZINE TABLET - _When you must not use it _ _ _ Do not take this medicine if: • You are hypersensitive to, or have had an allergic reaction to promethazine or any of the ingredients listed at the end of this leaflet. • you have glaucoma (increased eye pressure) • you have central nervous system depression such as decreased breathing rate, heart rate • You use in premature infants or neonates • You are taking a class of medicine known as _'monoamine _ _oxidase _ inhibitors' (MAOIs) (often taken for depression), or you have taken such a medici Læs hele dokumentet
A 6.5mm, round convex core tablet, film coated blue, one side marked ‘UP’ and scored, the other side plain. Each tablet contains Promethazine HCI 25mg As symptomatic treatment for allergic conditions of the upper respiratory tract and skin including allergic rhinitis, urticaria and anaphylactic reactions to drugs and foreign proteins. As an adjunct in preoperative sedation in surgery and obstetrics. As an antiemetic. For short term use: Sedation and treatment of insomnia in adults. As a paediatric sedative. Promethazine is a phenothiazine-derivative antihistamine which acts by blocking the action of histamine through competitive, reversible inhibition of H 1 receptor sites on tissues; it does not inactivate histamine or prevent its synthesis or release. It thereby prevents, but does not reverse responses mediated by histamine alone. Histamine H 1 receptors are responsible for vasodilation, increased capillary permeability, flare and itch reactions in the skin, and to some extent for contraction of smooth muscle in the bronchial and gastrointestinal tract. Thus, blockage of H 1 receptors may inhibit these reactions. In addition, its anticholin- ergic effects which mediates via muscarinic receptors provide a drying effect on the nasal and oral mucosa. The mechanism by which promethazine exerts its antiemetic, anti-motion sickness, and anti-vertigo effects is not precisely known but may be relatcd to its centrally anticholinergic actions, It diminishes vestibular stimulation and depresses labyrinthine function. Activity on the medullary chemoreceptive trigger zone may also be involved in the antiemetic effect. Promethazine crosses the blood-brain-barrier and produces sedation due to the inhibition of histamine N- methyl transferase and blockage of central histaminer- gic receptors. Antagonism of other central nervous system receptor sites, such as those for serotonin, acetylcholine, and alpha-adrenergic stimulation, may also be involved. Promethazine are thought to cause indirect reduction of stimuli to the brai Læs hele dokumentet