Land: Sydafrika
Sprog: engelsk
Kilde: South African Health Products Regulatory Authority (SAHPRA)
Lennon
OXYMYCIN* CAPSULES SCHEDULING STATUS: S4 PROPRIETARY NAME (and dosage form): OXYMYCIN* CAPSULES COMPOSITION: Each capsule contains: Oxytetracycline Hydrochloride equivalent to 250 mg Oxytetracycline base. Contains Tartrazine PHARMACOLOGICAL CLASSIFICATION: A 20.1.1 Broad and medium spectrum antibiotics. PHARMACOLOGICAL ACTION: Oxytetracycline is a bacteriostatic antibiotic and inhibits bacterial protein synthesis (30S ribosomes). It is particularly effective in vitro against the following organisms (in vitro activity does not necessarily imply in vivo efficacy): Vibrio cholerae, Ureaplasma urealyticum, Mycoplasma pneumoniae, Chlamydia trachomatis, Chlamydia psittaci, Borrelia recurrensis, Calymmatobacterium granulomatis, Borrelia burgdorferi, penicillin-sensitive Neisseria gonorrhoea and Rickettsiae; Oxytetracycline is also effective against the following organisms in vitro: Clostridium tetani, Listeria monocytogenes, Haemophilus ducreyi, Campylobacter jejuni, Leptospira, Actinomyces israelii, Bacillus anthracis*, Pasteurella multocida, Streptobaccillus moniliformis, Erysipelothrix rhusiopathiae. Oxytetracycline may also show some effect against the following organisms: Bacteroides species and Fusobacterium nucleatum. * = in vitro sensitivity tests must be performed. Resistant pathogens: Many strains of the following are resistant: Staphylococci, Enterococci, Proteus vulgaris, Fungi and yeasts (except Actinomyces), Pseudomonas aeruginosa (all strains), E. coli, Shigella, Strep. pneumoniae. Oxytetracycline is adequately but incompletely absorbed from the intestinal tract. Effective blood levels are reached in about two to four hours after oral administration and are maintained with the recommended dosages. Absorption is diminished by the presence of iron, aluminium, calcium and magnesium and milk products. Oxytetracycline is Læs hele dokumentet