Land: Sydafrika
Sprog: engelsk
Kilde: South African Health Products Regulatory Authority (SAHPRA)
Lennon
MITIL TABLETS SCHEDULING STATUS: S5 PROPRIETARY NAME (and dosage form): MITIL TABLETS COMPOSITION: Each tablet contains: Prochlorperazine Maleate 5 mg PHARMACOLOGICAL CLASSIFICATION: A 2.6 Phenothiazines and derivatives PHARMACOLOGICAL ACTION: Prochlorperazine, like its related molecules chlorpromazine and trifluoperazine, is a psychotherapeutic agent believed to act at the subcortical level of the brain, principally it depresses the central nervous system. Prochlorperazine is more potent than chlorpromazine but less so than trifluoperazine. The depressant action, hypotensive effect, antimuscarinic activity, potentiation of central nervous system depressants, and antihistaminic activity of prochlorperazine are all less than the respective effects of chlorpromazine. INDICATIONS: Prochlorperazine tablets are used in the control of mild and moderate mental and emotional disturbances, characterised by anxiety, tension and agitation. These tablets are used in the treatment of Ménière's syndrome, labyrinthitis, vertigo and migraine. It is also particularly effective for the prevention and treatment of nausea and vomiting. CONTRA-INDICATIONS: Contra-indicated in patients with pre-existing central nervous system depression or coma, bone marrow suppression, or phaechromocytoma. Central nervous system depression may be enhanced by other drugs with central nervous system- depressant properties including, alcohol, general anaesthetics, hypnotics and sedatives, and opioid anaesthetics. Phenothiazines effects on the vomiting centre may mask the symptoms of overdosage of other agents, or of disorders such as gastro-intestinal obstruction. Should not be given to children weighing under 10 kg. Safely in pregnancy and lactation has not yet been established therefore prochlorperazine is best avoided. WARNINGS: Læs hele dokumentet