Land: Australien
Sprog: engelsk
Kilde: Department of Health (Therapeutic Goods Administration)
hydrochlorothiazide,irbesartan
Arrow Pharma Pty Ltd
Hydrochlorothiazide,Irbesartan
Registered
1 KSART HCT _contains the active ingredients irbesartan and hydrochlorothiazide_ CONSUMER MEDICINE INFORMATION What is in this leaflet This leaflet answers some common questions about KSART HCT. It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you taking KSART HCT against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, TALK TO YOUR DOCTOR OR PHARMACIST. Keep this leaflet with your medicine. You may need to read it again. What KSART HCT is used for KSART HCT lowers high blood pressure, also called hypertension. Everyone has blood pressure. This pressure helps get your blood all around your body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have hypertension (high blood pressure) which means your blood pressure stays high, even when you are calm and relaxed. There are usually no symptoms of high blood pressure. The only way of knowing that you have hypertension is to have your blood pressure checked on a regular basis. High blood pressure, if not treated, can damage blood vessels in several organs such as the heart, the kidneys, the brain and the eyes. This may lead to heart attacks, heart or kidney failure, strokes, or blindness. There are usually no symptoms of high blood pressure before damage occurs, so your doctor needs to measure your blood pressure to see if it is too high. High blood pressure can be treated and controlled with medicines such as KSART HCT. Your doctor may also have recommended that you adjust your lifestyle to help to lower your high blood pressure (losing weight, avoiding smoking, reducing alcohol consumption and restricting the amount of salt in the diet). Your doctor may also have encouraged the practice of regular, mild (not strenuous) exercise such as walking, swimming, etc. KSART HCT contains two medicines, irbesartan an Læs hele dokumentet
KSART ® HCT 150/12.5, 300/12.5, 300/25 (Irbesartan/Hydrochlorothiazide) Tablets PRODUCT INFORMATION NAMES OF THE MEDICINES IRBESARTAN The chemical name for irbesartan is 2-butyl-3-[(2’-(1_H_-tetrazol-5-yl)biphenyl-4-yl)methyl]-1,3- diazaspiro[4,4]non-1-en-4-one. Its structural formula is: C 25 H 28 N 6 O Molecular weight: 428.5 CAS No.: 138402-11-6 HYDROCHLOROTHIAZIDE The chemical name is 6-chloro-3,4-dihydro-2_H_-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. Its structural formula is: C 7 H 8 ClN 3 O 4 S 2 Molecular weight: 297.7 CAS No.: 58-93-5 DESCRIPTION Irbesartan is a white or almost white crystalline powder. It is practically insoluble in water, sparingly soluble in methanol and slightly soluble in methylene chloride. Hydrochlorothiazide is a white or almost white, crystalline powder. It is very slightly soluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides. Page 2 of 16 KSART HCT – Product Information KSART HCT tablets come in three strengths and contain 150 mg of irbesartan and 12.5 mg of hydrochlorothiazide, 300 mg of irbesartan and 12.5 mg of hydrochlorothiazide or 300 mg of irbesartan and 25 mg of hydrochlorothiazide. The tablets also contain mannitol, povidone, microcrystalline cellulose, croscarmellose sodium, silica colloidal anhydrous, magnesium stearate, Opadry II complete film coating system 85F34353 Pink (ARTG 107713; 150 mg/12.5 mg strength), Opadry II complete film coating system 85F342 29 Pink (ARTG 107715; 300 mg/12.5 mg strength) and Opadry II complete film coating system 85F34230 Dark Pink (ARTG 107714; 300 mg/25 mg strength). The tablets are gluten free. PHARMACOLOGY KSART HCT (irbesartan/hydrochlorothiazide) is an oral antihypertensive agent combining a nonpeptide angiotensin II receptor (AT1-subtype) antagonist, irbesartan, and a thiazide diuretic, hydrochlorothiazide. Irbesartan is a specific antagonist of angiotensin II receptors (AT1-subtype). Angiotensin II is an important component of the r Læs hele dokumentet