Land: New Zealand
Sprog: engelsk
Kilde: Medsafe (Medicines Safety Authority)
Foscarnet sodium hexahydrate 24 mg/mL
Link Pharmaceuticals Ltd
Foscarnet sodium hexahydrate 24 mg/mL
24 mg/mL
Solution for infusion
Active: Foscarnet sodium hexahydrate 24 mg/mL
Bottle, glass, 250 mL
Prescription
Prescription
PCAS Finland Oy
Treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS). Treatment of acyclovir resistant herpes simplex virus (HSV) infections in immunocompromised patients. The safety and efficacy of Foscavir for the treatment of other HSV infections (e.g. retinitis, encephalitis); congenital or neonatal disease; or HSV in immunocompetent individuals has not been established.
Package - Contents - Shelf Life: Bottle, glass, - 250 mL - 24 months from date of manufacture stored at or below 25°C
1988-06-08
FOSCAVIR ® INJECTION 1 FOSCAVIR ® INJECTION _Foscarnet sodium. _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some of the common questions people ask about Foscavir. It does not contain all the information that is known about Foscavir. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor will have weighed the risks of you being given Foscavir against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT BEING GIVEN THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT IS FOSCAVIR USED FOR Foscavir is used to treat infections caused by two viruses, Cytomegalovirus (CMV) and Herpes simplex. These viruses infect different parts of the body and are most serious if your body's natural defences to fight disease are low (immunocompromised). Your doctor will have explained what type of infection you have and where it is. Foscavir belongs to a group of medicines called antivirals. It is injected into the body where it interferes with the way viral cells reproduce themselves and stops them increasing in number. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY THIS MEDICINE HAS BEEN PRESCRIBED FOR YOU. Your doctor may prescribe this medicine for another use. Foscavir is not addictive. It is only available with a doctor's prescription. There is not enough information to recommend the use of Foscavir in children. BEFORE YOU ARE GIVEN FOSCAVIR _WHEN YOU MUST NOT BE GIVEN _ _IT _ DO NOT USE FOSCAVIR IF YOU HAVE AN ALLERGY TO: • foscarnet • any of the ingredients listed at the end of this leaflet. SOME OF THE SYMPTOMS OF AN ALLERGIC REACTION MAY INCLUDE: • shortness of breath • wheezing or difficulty breathing • swelling of the face, lips, tongue, or other parts of the body • rash, itching or hives of the skin TELL YOUR DOCTOR BEFORE YOU ARE GIVEN FOSCAVIR IF YOU ARE PREGNANT, INTEND TO BECOME PREGNANT, ARE BREAST-FEEDING OR INTEN Læs hele dokumentet
FOSCAVIR Infusion Data Sheet Page 1 of 14 NEW ZEALAND DATA SHEET 1. FOSCAVIR® 24 MG/ML SOLUTION FOR INFUSION. 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Foscarnet trisodium hexahydrate 24 mg/mL 3. PHARMACEUTICAL FORM Solution for infusion. A clear, colourless, particle-free, sterile, isotonic solution (pH 7.4) containing 24 mg/mL (80 µmol/mL) foscarnet trisodium hexahydrate, hydrochloric acid q.s. and water q.s. 4. CLINICAL PARTICULARS 4.1. THERAPEUTIC INDICATIONS • Treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS). • Treatment of aciclovir resistant HSV infections in immunocompromised patients. The safety and efficacy of FOSCAVIR for the treatment of other HSV infections (e.g. retinitis, encephalitis); congenital or neonatal disease; or HSV in immunocompetent individuals has not been established. 4.2. DOSE AND METHOD OF ADMINISTRATION Contact with the skin and eyes may cause local irritation and a burning sensation. If accidental contact occurs, the exposed area should be rinsed immediately with cold water. METHOD OF ADMINISTRATION FOSCAVIR must be given by the intravenous route only, either via a central venous line or directly into peripheral veins. When peripheral veins are used, FOSCAVIR 24 mg/mL must be diluted with glucose (dextrose) 5% or normal saline to a concentration of 12 mg/mL immediately prior to administration. (See SECTION 4.4 SPECIAL WARNINGS AND PRECAUTIONS FOR USE regarding total daily sodium intake). FOSCAVIR 24 mg/mL solution may be given without dilution via a central vein. CAUTION - DO NOT ADMINISTER FOSCARNET BY RAPID INTRAVENOUS INJECTION. FOSCAVIR Infusion Data Sheet Page 2 of 14 ADULTS CMV RETINITIS Induction therapy Foscarnet can be administered over 2-3 weeks, depending on clinical response, as intermittent infusions every 8 hours at a dose of 60 mg/kg in patients with normal renal function (see dosing chart below). The infusion time should not be shorter than one hour for the 60 mg/kg dose. The dose of foscarnet should be Læs hele dokumentet