Land: New Zealand
Sprog: engelsk
Kilde: Medsafe (Medicines Safety Authority)
Fexofenadine hydrochloride 180mg; Fexofenadine hydrochloride 180mg
Douglas Pharmaceuticals Limited
Fexofenadine hydrochloride 180 mg
180 mg
Film coated tablet
Active: Fexofenadine hydrochloride 180mg Excipient: Croscarmellose sodium Hyprolose Hypromellose Iron oxide red Iron oxide yellow Macrogol 400 Magnesium stearate Microcrystalline cellulose Opacode black S-1-8152HV Povidone Purified talc Purified water Titanium dioxide Active: Fexofenadine hydrochloride 180mg Excipient: Croscarmellose sodium Hyprolose Hypromellose Iron oxide red Iron oxide yellow Macrogol 400 Magnesium stearate Microcrystalline cellulose Opacode black S-1-27794 Povidone Purified talc Purified water Titanium dioxide
Blister pack, PVC/PVDC/Al foil, 10 tablets
Pharmacy only
Pharmacy only
Sun Pharmaceutical Industries Ltd
Package - Contents - Shelf Life: Blister pack, PVC/PVDC/Al foil - 10 tablets - 36 months from date of manufacture stored at or below 25°C - Blister pack, PVC/PVDC/Al foil - 30 tablets - 36 months from date of manufacture stored at or below 25°C
2004-06-23
DATA SHEET FEXOFENADINE Fexofenadine Tablets PRESENTATION Fexofenadine 120 mg Tablets are pink coloured, capsule- shaped film coated tablets imprinted with "F1" in black ink on one side and plain on the other side containing 120 mg fexofenadine hydrochloride. Fexofenadine 180 mg Tablets are pink coloured, capsule- shaped film coated tablets imprinted with "F2" in black ink on one side and plain on the other side containing 180 mg fexofenadine hydrochloride. USES Fexofenadine hydrochloride is the synthetic hydrochloride salt of fexofenadine, the carboxylic acid metabolite of terfenadine (Teldane). It is an orally active non-sedating H 1 -receptor antagonist and is effective for the relief of symptoms associated with seasonal allergic rhinitis (sneezing, rhinorrhea, pruritus and lacrimation). ACTIONS Fexofenadine is the major metabolite of terfenadine in man and is largely responsible for the antihistaminic effect following the administration of terfenadine. The antihistaminic effects of fexofenadine have been demonstrated in animal systems _in vitro _and _in vivo_. Oral administration of fexofenadine to guinea pigs indicated that fexofenadine antagonised histamine-induced skin wheals in a dose-dependent manner. The antihistaminic effects of fexofenadine and terfenadine were also assessed in the isolated guinea pig ileum _in vitro_. Both drugs antagonised the contractile effects of histamine, however, fexofenadine was found to be a more selective histamine antagonist than terfenadine. Fexofenadine inhibited antigen induced bronchospasm in sensitised guinea pigs and at high doses inhibited histamine release from peritoneal mast cells of the rat. In laboratory animals, no anticholinergic or alpha-1-adrenergic receptor blocking effects were observed. Radiolabelled tissue distribution studies in rat indicated that fexofenadine did not cross the blood brain barrier. Fexofenadine is not associate Læs hele dokumentet