Land: Malaysia
Sprog: engelsk
Kilde: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
CLARITHROMYCIN
RANBAXY (MALAYSIA) SDN. BHD.
CLARITHROMYCIN
10Tablet Tablets
Sun Pharmaceutical Industries Limited
CRIXAN OD TABLET Page 1 CRIXAN OD TABLETS _ _ Clarithromycin Extended Release Tablets 500 mg Consumer Medication Information Leaflet (RiMUP) WHAT IS IN THIS LEAFLET 1. What CRIXAN OD TABLET is used for 2. How CRIXAN OD TABLET works 3. Before you use CRIXAN OD TABLET 4. How to use CRIXAN OD TABLET 5. While you are using it 6. Side Effects 7. Storage and disposal of CRIXAN OD TABLET 8. Product description 9. Manufacturer and Product registration holder 10. Date of revision This leaflet answers some common questions about CRIXAN OD TABLET . It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. Each CRIXAN OD TABLET contains 500 mg of the active ingredient Clarithromycin. All medicines have risks and benefits. Your doctor has weighed the risks of you taking clarithromycin against the benefits it is expected to have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT CRIXAN OD TABLET IS USED FOR CRIXAN OD TABLET IS USED TO TREAT INFECTIONS SUCH AS : Chest infections such as bronchitis and pneumonia Throat and sinus infections Skin and tissue infections, e.g. cellulitis, folliculitis or erysipelas. CRIXAN OD TABLET is used in adults and children 12 years and older. HOW CRIXAN OD TABLET WORKS CRIXAN belongs to a group of medicines called macrolide antibiotics. Antibiotics stop the growth of bacteria (bugs) which cause infections. BEFORE YOU USE CRIXAN OD TABLET _WHEN YOU MUST NOT USE IT _ _ _ DO NOT TAKE CRIXAN OD TABLET IF YOU: know that you are allergic to clarithromycin, other macrolide antibiotics such as erythromycin or azithromycin, or any of the other ingredients in the tablets. are taking medicines called ergot alkaloid tablets (e.g. ergotamine or dihydroergotamine) or use ergotamine inhalers for migraine. are taking medicines called terfenadine or astemizole (widely taken for hay fever or allergies) or cisapride Læs hele dokumentet
_For the use only of a Registered Medical Practitioner _ PRESCRIBING INFORMATION CRIXAN OD 500 MG TABLETS (Clarithromycin Extended Release Tablets) COMPOSITION CRIXAN OD 500 MG TABLETS Each extended release tablet contains: Clarithromycin…………………500 mg _EXCIPIENTS_: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Povidone, Colloidal Anhydrous Silica, Lactose, Sodium Stearyl Fumarate, Magneisium Stearate, Isopropyl Alcohol, Purified Talc, Opadry Y 20 H 52875,Opacode Black S-1-17823 DESCRIPTION CRIXAN OD 500 MG TABLETS contains clarithromycin in extended release formulation. Clarithromycin is a semi-synthetic macrolide antibiotic obtained by substitution of a CH 3 O group for the hydroxyl (OH) group at position 6 of the erythromycin lactonic ring. Specifically clarithromycin is 6-Omethyl erythromycin A. Its molecular weight is 747.96. The white to off-white antibiotic powder is bitter, practically odourless, soluble in acetone and in methylene chloride, slightly soluble in methanol, practically insoluble in water. PRODUCT DESCRIPTION Pale yellow coloured, oval, biconvex, film coated tablets printed with CLNXL in black ink on one side and plain on the other. PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES PHARMACODYNAMICS Pharmacotherapeutic group: Antibacterial for systemic use, macrolide ATC-Code: J01FA09 MECHANISM OF ACTION Clarithromycin exerts its antibacterial action by binding to the 5OS ribosomal subunits of susceptible bacteria and suppressing protein synthesis. Clarithromycin has demonstrated excellent _in vitro _activity against both standard strains of bacteria and clinical isolates. It is highly potent against a wide variety of aerobic and anaerobic Gram- positive and Gram-negative organisms. The minimum inhibitory concentrations (MIC's) of clarithromycin are generally one log2 dilution more potent than the MIC's of erythromycin. Clarithromycin has excellent activity against _Legionella _ _pneumophila_, and _Mycoplasma _ _pneumoniae_. It is bactericidal to _ Helicobacter pylor Læs hele dokumentet