ZOVIRAX IV INJECTION

Země: Jihoafrická republika

Jazyk: angličtina

Zdroj: South African Health Products Regulatory Authority (SAHPRA)

Dostupné s:

GlaxoSmithKline South Africa (Pty) Limited

Dávkování:

See ingredients

Léková forma:

INJECTION

Složení:

EACH VIAL CONTAINS ACICLOVIR SODIUM EQUIVALENT TO ACICLOVIR 250 mg

Stav Autorizace:

Registered

Datum autorizace:

1984-09-01

Informace pro uživatele

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ZOVIRAX IV
PATIENT INFORMATION LEAFLET
SCHEDULING STATUS:
S4
ZOVIRAX
IV INJECTION
ACYCLOVIR 250 MG PER VIAL
READ ALL OF THIS LEAFLET CAREFULLY BEFORE YOU ARE GIVEN ZOVIRAX IV.
•
Keep this leaflet. You may need to read it again.
•
If you have further questions, please ask your doctor or your
pharmacist.
•
ZOVIRAX IV has been prescribed for you personally and you should not
pass it on to others.
It may harm them, even if their symptoms are the same as yours.
WHAT IS IN THIS LEAFLET:
1. What ZOVIRAX IV is and what it is used for
2. What you need to know before you use ZOVIRAX IV
3. How to use ZOVIRAX IV
4. Possible side effects
5. How to store ZOVIRAX IV
6. Contents of the pack and other information.
1. WHAT ZOVIRAX IV IS AND WHAT IT IS USED FOR:
ZOVIRAX is an antiviral agent.
ZOVIRAX is used to treat herpes encephalitis, shingles and chicken
pox.
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ZOVIRAX is also used to treat herpes simplex infections and to prevent
recurrent attacks of
herpes simplex infections in people whose immune systems are weakened.
ZOVIRAX prevents a virus called cytomegalovirus (CMV) in people who
have had a bone
marrow transplant.
2. WHAT YOU NEED TO KNOW BEFORE YOU USE ZOVIRAX IV:
ZOVIRAX IV SHOULD NOT BE ADMINISTERED TO YOU:
•
if you have an allergy to, or if you have previously experienced an
allergic reaction to
acyclovir, or valaciclovir.
WARNINGS AND PRECAUTIONS:
TAKE SPECIAL CARE WITH ZOVIRAX IV:
Tell your doctor or healthcare provider before being given the
injection if:
•
you are pregnant or trying to become pregnant
•
you are breastfeeding or planning to breastfeed
•
you suffer from kidney or liver disease
•
if you are elderly.
If you are elderly or if you have kidney problems, it is important
that you drink adequate fluids
whilst you are having treatment. The doctor will monitor you closely
as there is a risk of
experiencing nervous system side effects (see section 4).
If any of the above applies to you or if you are unsure if they apply
to you, and if you have not
already discussed with

Charakteristika produktu

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GDS-30
ZOVIRAX IV
PROFESSIONAL INFORMATION
SCHEDULING STATUS:
S4
1.
NAME OF MEDICINE:
ZOVIRAX IV Injection
Powder for Injection
Acyclovir 250 mg
2.
QUALITATIVE AND QUANTITATIVE COMPOSITION:
Each vial supplies acyclovir 250 mg as the freeze-dried sodium salt.
The sodium ion content is approximately 26 mg per vial.
3. PHARMACEUTICAL FORM:_ _
Powder for Injection
Vial containing a white to off-white powder.
4.
CLINICAL PARTICULARS:
4.1
INDICATIONS:
I
Herpes simplex infections in immunocompromised patients:
ZOVIRAX IV is indicated for the treatment of herpes simplex
infections.
ZOVIRAX IV is indicated for the prophylaxis of herpes simplex
infections in patients.
II
ZOVIRAX IV is indicated in the treatment of varicella zoster
infections in immuno-
compromised patients:
Chickenpox - prophylaxis and therapy of pneumonial complications.
Shingles - only if the lesions are not older than 72 hours.
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GDS-30
III
ZOVIRAX IV is indicated for treatment of herpes simplex infections in
the neonate.
IV
ZOVIRAX IV is indicated for the treatment of herpes simplex
encephalitis.
V
ZOVIRAX IV is indicated for the prevention of reactivation of
cytomegalovirus
infection in seropositive patients following bone marrow
transplantation.
4.2
POSOLGY AND METHOD OF ADMINISTRATION:
The required dose of ZOVIRAX IV should be administered by slow
intravenous infusion
over a one hour period.
A course of treatment with ZOVIRAX IV usually lasts 5 days, but this
may be adjusted
according to the patient's condition and response to therapy.
Treatment for herpes encephalitis usually lasts 10 days. Treatment for
neonatal herpes usually lasts 14-21 days. The duration of prophylactic
administration of ZOVIRAX IV is determined by the duration of the
period at risk.
DOSAGE IN ADULTS:
INDICATION
IMMUNE STATUS
DOSAGE
Herpes simplex infection
(except herpes
encephalitis)
Immunocompromised
5 mg/kg body weight every
8 hours
Varicella zoster infection
Immunocompromised
(normal renal function)
10 mg/kg body weight every
8 hours
Herpes simplex