Země: Austrálie
Jazyk: angličtina
Zdroj: Department of Health (Therapeutic Goods Administration)
carvedilol
Fair-Med Healthcare Australia Pty Ltd
Carvedilol
Registered
VOLIROP CONSUMER MEDICINE INFORMATION Ver 1.1 Page 1 of 5 VOLIROP 3.125, 6.25, 12.5 & 25 Carvedilol CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about VOLIROP. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking VOLIROP against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT VOLIROP USED FOR VOLIROP contains the active ingredient carvedilol. VOLIROP is used to treat • heart failure, • high blood pressure, which is called hypertension. VOLIROP belongs to a group of medicines called beta-blockers. These medicines work by relaxing tightened blood vessels and slowing the heart rate. VOLIROP has the additional effect of being an antioxidant. HEART FAILURE: Heart failure occurs when the heart can no longer pump blood strongly enough for the body's needs. Often the heart grows in size to try to improve the blood flow but this can make the heart failure worse. Symptoms of heart failure include shortness of breath and swelling of the feet or legs due to fluid build-up. VOLIROP reduces the pressure that the heart has to pump against as well as controlling your heart rate. Over 6 months or more this will reduce the size of an oversized heart and increase its efficiency. VOLIROP reduces the chances of you being admitted to hospital and/ or dying from this condition. VOLIROP is often used with other medicines to treat heart failure. HYPERTENSION: All people have blood pressure. This pressure helps to push blood all around your body. Your blood pressure changes during the day, depending on how busy you are or how you are feeling. You have hypertension (high blood pressure) when your blood pressure stays higher than is needed, even when you are calm and relaxed. Regula Přečtěte si celý dokument
Product Information: VOLIROP (Carvedilol Tablets 3.125, 6.25, 12.5 & 25 mg) Ver 1.2 Page 1 of 22 PRODUCT INFORMATION VOLIROP 3.125 (3.125MG CARVEDILOL TABLETS) VOLIROP 6.25 (6.25MG CARVEDILOL TABLETS) VOLIROP 12.5 (12.5MG CARVEDILOL TABLETS) VOLIROP 25 (25MG CARVEDILOL TABLETS) NAME OF THE MEDICINE The name of the medicine is carvedilol. O H N O HN OCH 3 H OH CHEMICALNAME: (2RS)-1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]propan- 2-ol MOLECULAR FORMULA: C 24 H 26 N 2 O 4 MOLECULAR WEIGHT: 406.5 CAS REGISTRY NUMBER: _[72956–09–3] _ DESCRIPTION Carvedilol is a white or almost white, crystalline powder. It is slightly soluble in alcohol, practically insoluble in water and dilute acids. VOLIROP is available as tablets containing 3.125, 6.25, 12.5 & 25 mg of carvedilol. _VOLIROP 3.125 _ White to off-white, oval shaped, film-coated tablets debossed with ‘E’ on one side and ‘01’ on the other side. _ _ _VOLIROP 6.25_ White to off-white, oval shaped, film-coated tablets debossed with ‘F 57’ on one side and deep break line on the other side. _ _ _VOLIROP 12.5_ White to off-white, oval shaped, film-coated tablets debossed with ‘F 58’ on one side and deep break line on the other side. _ _ Product Information: VOLIROP (Carvedilol Tablets 3.125, 6.25, 12.5 & 25 mg) Ver 1.2 Page 2 of 22 _VOLIROP 25_ White to off-white, oval shaped, film-coated tablets debossed with ‘F 59’ on one side and deep break line on the other side. VOLIROP tablets contain the following inactive ingredients: Lactose, colloidal anhydrous silica, crospovidone (Type A & Type B), povidone, sucrose, magnesium stearate, macrogol 400, polysorbate 80, titanium dioxide & hypromellose. PHARMACOLOGY PHARMACODYNAMICS Carvedilol is a dual action cardiovascular agent; a vasodilating, non-selective beta-blocking agent with antioxidant properties. Vasodilation has been shown to be mediated primarily by selective blockade of alpha 1 -adrenoreceptors. Carvedilol is a racemic mixture. In animal models, both enantiomers have alpha-adre Přečtěte si celý dokument