TRIHEXYPHENIDYL HYDROCHLORIDE tablet

Země: Spojené státy

Jazyk: angličtina

Zdroj: NLM (National Library of Medicine)

Aktivní složka:

TRIHEXYPHENIDYL HYDROCHLORIDE (UNII: AO61G82577) (TRIHEXYPHENIDYL - UNII:6RC5V8B7PO)

Dostupné s:

Richmond Pharmaceuticals, Inc.

INN (Mezinárodní Name):

TRIHEXYPHENIDYL HYDROCHLORIDE

Složení:

TRIHEXYPHENIDYL HYDROCHLORIDE 2 mg

Podání:

ORAL

Druh předpisu:

PRESCRIPTION DRUG

Terapeutické indikace:

Trihexyphenidyl HCl tablets are indicated as an adjunct in the treatment of all forms of parkinsonism (postencephalitic, arteriosclerotic, and idiopathic). It is often useful as adjuvant therapy when treating these forms of parkinsonism with levodopa. Additionally, it is indicated for the control of extrapyramidal disorders caused by central nervous system drugs such as the dibenzoxazepines, phenothiazines, thioxanthenes, and butyrophenones.

Přehled produktů:

Trihexyphenidyl HCl tablets are available as follows: 2 mg – round, flat, scored, white tablets; debossed "5971" above the score and "V" below the score. Available in bottles of 100, 500 and 1000. 5 mg – round, flat, scored, white tablets; debossed "5972" above the score and "V" below the score. Available in bottles of 100, 500, and 1000.

Stav Autorizace:

Abbreviated New Drug Application

Charakteristika produktu

TRIHEXYPHENIDYL HYDROCHLORIDE- TRIHEXYPHENIDYL HYDROCHLORIDE TABLET
RICHMOND PHARMACEUTICALS, INC.
----------
TRIHEXYPHENIDYL
HYDROCHLORIDE TABLETS, USP
RX ONLY
DESCRIPTION
Trihexyphenidyl HCl is a synthetic antispasmodic. Each tablet for oral
administration, contains 2 mg or
5 mg trihexyphenidyl HCl, each strength also containing as inactive
ingredients: magnesium stearate,
microcrystalline cellulose, and sodium starch glycolate.
Trihexyphenidyl HCl is a white or slightly off white, crystalline
powder, having not more than a very
faint odor.
Trihexyphenidyl HCl is the substituted piperidine salt,
1-piperidinepropanol,α-cyclohexyl-α-phenyl-
,hydrochloride,(±)-. The structural formula is:
CLINICAL PHARMACOLOGY
Trihexyphenidyl exerts a direct inhibitory effect upon the
parasympathetic nervous system. It also has a
relaxing effect on smooth musculature; exerted both directly upon the
muscle tissue itself and indirectly
through an inhibitory effect upon the parasympathetic nervous system.
Its therapeutic properties are
similar to those of atropine, although undesirable side effects are
ordinarily less frequent and severe
than with the latter.
INDICATIONS AND USAGE
Trihexyphenidyl HCl tablets are indicated as an adjunct in the
treatment of all forms of parkinsonism
(postencephalitic, arteriosclerotic, and idiopathic). It is often
useful as adjuvant therapy when treating
these forms of parkinsonism with levodopa. Additionally, it is
indicated for the control of
extrapyramidal disorders caused by central nervous system drugs such
as the dibenzoxazepines,
phenothiazines, thioxanthenes, and butyrophenones.
WARNINGS
Patients to be treated with trihexyphenidyl HCl should have a
gonioscope evaluation and close
monitoring of intraocular pressures at regular periodic intervals.
PRECAUTIONS
Although trihexyphenidyl HCl is _not_ contraindicated for patients
with cardiac, liver, or kidney
disorders, or with hypertension, such patients should be maintained
under close observation.
Since the use of trihexyphenidyl HCl may, in so