Země: Spojené státy
Jazyk: angličtina
Zdroj: NLM (National Library of Medicine)
cloprostenol sodium (UNII: 886SAV9675) (cloprostenol - UNII:4208238832)
Merial, Inc.
cloprostenol sodium
cloprostenol 250 ug in 1 mL
INTRAMUSCULAR
PRESCRIPTION
INDICATIONS: For intramuscular use to induce luteolysis in beef and dairy cattle. The luteolytic action of SYNCHSURE can be utilized to manipulate the estrous cycle to better fit certain management practices, to terminate pregnancies resulting from mismatings, and to treat certain conditions associated with prolonged luteal function. CONTRAINDICATIONS: SYNCHSURE should not be administered to a pregnant animal whose calf is not to be aborted.
HOW SUPPLIED: 100mL multidose vial
Abbreviated New Animal Drug Application
SYNCHSURE- CLOPROSTENOL SODIUM INJECTION, SOLUTION MERIAL, INC. ---------- SYNCHSURE™ (CLOPROSTENOL SODIUM) ANADA 200-310, Approved by FDA PROSTAGLANDIN ANALOGUE FOR CATTLE Equivalent to 250 mcg cloprostenol/mL CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION: SYNCHSURE™ (cloprostenol sodium) is a synthetic prostaglandin analogue structurally related to prostaglandin F (PGF ). Each mL of the colorless aqueous solution contains 263 mcg of cloprostenol sodium (equivalent to 250 mcg of cloprostenol), chlorocresol 1.0 mg as a bactericide, citric acid anhydrous 0.66 mg, sodium citrate 5.03 mg, sodium chloride 6.76 mg. The pH is adjusted, as necessary, with sodium hydroxide or citric acid. ACTION: SYNCHSURE causes functional and morphoIogical regression of the _corpus luteum_ (luteolysis) in cattle. In normal, nonpregnant cycling animals, this effect on the life span of the _corpus luteum_ usually results in estrus 2 to 5 days after treatment. In animals with prolonged luteal function (pyometra, mummified fetus, and luteal cysts), the induced luteolysis usually results in resolution of the condition and return to cyclicity. Pregnant animals may abort depending on the stage of gestation. INDICATIONS: For intramuscular use to induce luteolysis in beef and dairy cattle. The luteolytic action of SYNCHSURE can be utilized to manipulate the estrous cycle to better fit certain management practices, to terminate pregnancies resulting from mismatings, and to treat certain conditions associated with prolonged luteal function. RECOMMENDED USES: UNOBSERVED OR NONDETECTED ESTRUS Cows which are not detected in estrus, although ovarian cyclicity continues, can be treated with 2α 2α SYNCHSURE if a mature _corpus luteum_ is present. Estrus is expected to occur 2 to 5 days following injection, at which time animals may be inseminated. Treated cattle should be inseminated at the usual time following detection of estrus. If estrus detection is not desirable or possible, treat Přečtěte si celý dokument