Země: Malajsie
Jazyk: angličtina
Zdroj: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
HYDROCHLOROTHIAZIDE; LOSARTAN POTASSIUM
THE ZYFAS MEDICAL CO.,
HYDROCHLOROTHIAZIDE; LOSARTAN POTASSIUM
28 Tablets; 28 Tablets
IPCA LABORATORIES LIMITED
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ _PRESARTAN H 50/12.5MG FILM COATED TABLET _ Losartan Potassium, 50mg & Hydrochlorothiazide Tablets, 12.5mg 1 WHAT IS IN THIS LEAFLET: 1. What Presartan H 50 is used for 2. How Presartan H 50 works 3. Before you take Presartan H 50 4. How to take Presartan H 50 5. While you are using Presartan H 50 6. Side effects 7. After using Presartan H 50 8. Product Description 9. Manufacturer & Product Registration Holder WHAT PRESARTAN H 50 IS USED FOR Presartan H 50 is indicated for the treatment of essential hypertension (high blood pressure). Presartan H 50 is a combination of an angiotensin II receptor antagonist (losartan) and a diuretic (hydrochlorothiazide). HOW PRESARTAN H 50 WORKS It is a medicine used to treat high blood pressure. Losartan relaxes your blood vessels and thus lowers your blood pressure, whereas hydrochlorothiazide works by making your kidneys pass more water and salt. BEFORE YOU TAKE PRESARTAN H 50 _When you must not take it _ You should not take this medicine when: • you are allergic (hypersensitive) to losartan, hydrochlorothiazide or to any of the other ingredients in this medicine • you are allergic (hypersensitive) to other sulfonamide-derived substances (e.g. other thiazides, some antibacterial drugs such as co- trimoxazole, ask your doctor if you are not sure) • you are, think you may be or are planning to become pregnant • your kidneys are not producing any urine Inform your healthcare providers before taking Presartan H 50 if you have had skin cancer or if you develop an unexpected skin lesion during the treatment. Treatment with hydrochlorothiazide, particularly long term use with high doses, may increase the risk of some types of skin and lip cancer cancer (non-melanoma skin cancer). Protect your skin from sun exposure and UV rays while taking Presartan H 50 _Before you start to take it _ Check with your doctor before you take losartan and hydrochlorothiazide tablets: • if you are diabetic • if you have had gout • if you ha Přečtěte si celý dokument
_PRESARTAN H 50/12.5 _ Losartan Potassium & Hydrochlorothiazide 50 mg / 12.5 mg Film-Coated Tablets COMPOSITION Each film-coated tablet contains: Losartan potassium 50 mg Hydrochlorothiazide 12.5 mg PRODUCT DESCRIPTION Yellow coloured, oval, biconvex, film coated tablet. INDICATIONS Presartan H 50/12.5 Film Coated Tablets is indicated for the treatment of hypertension, for patients in whom combination therapy is appropriate. In hypertensive patients with left ventricular hypertrophy, a reduced risk of stroke was demonstrated with losartan administered usually in combination with hydrochlorothiazide. DOSAGE AND METHOD OF ADMINISTRATION Presartan H may be administered with other antihypertensive agents. Presartan H may be administered with or without food. Fixed dose combination is not indicated for initial therapy. HYPERTENSION The usual starting and maintenance dose of Presartan H 50/12.5 is one tablet of Presartan H 50/12.5 (losartan potassium 50 mg/hydrochlorothiazide 12.5 mg) once daily. For patients who do not respond adequately to Presartan H 50/12.5, the dosage may be increased to one tablet of Presartan H 50/12.5 (losartan potassium 100mg/hydrochlorothiazide 25mg) once daily or two tablets of Presartan H 50/12.5 once daily. The maximum dose is one tablet of Presartan H 50/12.5 once daily or two tablets of Presartan H 50/12.5 once daily. In general, the antihypertensive effect is attained within three weeks after initiation of therapy. Presartan H 50/12.5 (losartan potassium 100 mg/hydrochlorothiazide 12.5 mg) is available for those patients titrated to 100 mg of Losartan who require additional blood pressure control. Losartan Potassium should not be initiated in patients who are intravascularly volume- depleted (e.g., those treated with high-dose diuretics). Losartan Potassium is not recommended for patients with severe renal impairment (creatinine clearance ≤30 mL/min) or for patients with hepatic impairment. No initial dosage adjustment of Presartan H 50/12.5 is necessary for elderly patients. Presarta Přečtěte si celý dokument