Lipopharm® Capsule 300mg

Země: Malajsie

Jazyk: angličtina

Zdroj: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktivní složka:

Phospholipids from soya beans

Dostupné s:

IMEKS PHARMA SDN. BHD.

INN (Mezinárodní Name):

Phospholipids from soya beans

Jednotky v balení:

50Capsule Capsules; 100Capsule Capsules; 200Capsule Capsules

Výrobce:

R.P. SCHERER GMBH & CO KG

Charakteristika produktu

LIPOPHARM
® Capsule 300mg
1 soft gelatine capsule contains 300mg
phospholipids from soya beans.
PRODUCT DESCRIPTION
Gold-yellow
to
yellow-brown,
viscous
liquid
contained in colorless, transparent, oblong shaped,
11mm long soft gelatine shell.
PHARMACODYNAMICS
Phospholipid extract from soya beans consists of an
average
76%
phosphadylcholine
and
almost
exclusively of phosphoglycerides, with linoleic acid
predominating among the fatty acids.
Phosphatidylcholine is the major building block for
cell’s membrane and is vital in maintaining the cell-
membrane integrity that is essential for all biological
processes,
including
liver
metabolism.
Cell
membranes are vulnerable to damage by drugs,
toxins, and oxygen free radicals which subsequently
if not repaired, will lead to cell death.
The liver functions as major detoxification organ and
exposed
to
hepatotoxic
substance
attack
itself.
Severe damage to liver may impaired its ability to
regenerate
and
repair
any
damage
tissues
and
eventually
leading
to
various
liver
diseases.
Phosphatidylcholine protects the liver by inhibition
of peroxidative damage to liver’s cell membrane,
maintaining the basic homeostatic functional state
for
liver
cell
recovery
and
regeneration,
and
alleviate hepatic burden in phospholipids synthesis.
Phosphatidylcholine is also essential in production
of neurotransmitter, acetylcholine, which is required
in
maintaining
proper
functioning
of
brain
and
muscles movement. They are also involved in the
transportation of cholesterol in the bloodstream.
PHARMACOKINETICS
Phosphatidylcholine
is
absorbed
in
the
mucosal
cells of small intestine and broken down into lyso-
phosphatidylcholine.
In
the
intestinal
wall,
a
reacylation
of
lyso-phosphatidylcholine
to
phosphatidylcholine took place and is transported
via the lymphatics to the blood circulation.
Lyso-phosphatidylcholine is metabolized in the liver
to fatty acids, choline and glycerin-3-phosphate. In
the
plasma,
phosphatidylcholine
and
other
phosphoglycerides are tightly bound to lipoproteins
and/or