Flamazine 500g Jar

Země: Austrálie

Jazyk: angličtina

Zdroj: Department of Health (Therapeutic Goods Administration)

Aktivní složka:

Silver sulfadiazine

Dostupné s:

Smith & Nephew Pty Ltd

Léková forma:

Cream

Jednotky v balení:

1 Jar

Třída:

Medicine Registered

Terapeutické indikace:

Flamazine cream is indicated for the prevention of infection in severe burns. Other types of wounds, such as pressure sores and leg ulcers, may also benefit from the application of Flamazine cream.

Přehled produktů:

Flamazine is a sterile topical antibacterial cream containing silver sulfadiazine 1%.

Informace pro uživatele

FLAMAZINE Cream 

1 

FLAMAZINE™ Cream 
_ _
_silver sulfadiazine  _
_ _
Consumer Medicine Information 

What is in this leaflet ? 

This leaflet answers some 
common questions about 
FLAMAZINE.  It does not 
contain all of the available 
information.  

It does not take the place of 
talking to your doctor (or 
pharmacist). 

All medicines have risks and 
benefits. Your doctor _or _
_pharmacist _has weighed the 
risks of you using FLAMAZINE 
against the benefits they 
expect it will have for you. 

IF YOU HAVE ANY CONCERNS 
ABOUT THIS MEDICINE, ASK 
YOUR DOCTOR OR PHARMACIST. 

KEEP THIS LEAFLET WITH YOUR 
MEDICINE. You may need to 
read it again. 

What FLAMAZINE is 
used for 

FLAMAZINE is a topical 
antibacterial cream with an 
active ingredient which 
belongs to the group of 
antibiotic medicines called 
sulfonamides.  

FLAMAZINE is used to 
prevent  infection in severe 
burns. Other types of 
wounds, such as pressure 
sores and leg ulcers, may 
also benefit from the 
application of FLAMAZINE 
cream. 

• It is soothing when applied 
and has proven activity 
against a broad range of 
organisms including both 
Gram-positive and Gram-
negative bacteria and some 
viruses and fungi. 

Your doctor may have 
prescribed FLAMAZINE for 
another reason. 

ASK YOUR DOCTOR IF YOU HAVE 
ANY QUESTIONS ABOUT WHY 
FLAMAZINE HAS BEEN 
PRESCRIBED FOR YOU. 

This medicine is available 
only with a doctor’s 
prescription (except for 
Pharmacy-Only 50g tube in 
NZ). 

Before you use 
FLAMAZINE 
_ _
_WHEN YOU MUST NOT USE IT_ 

DO NOT USE FLAMAZINE IF: 

YOU HAVE AN ALLERGY TO: 

• FLAMAZINE or any 
medicine within the 
Sulfonamide group or any of 
the ingredients in FLAMAZINE 
listed at the end of this 
leaflet. 

ASK YOUR DOCTOR _OR _
_PHARMACIST _IF YOU ARE NOT 
SURE. 

DO NOT GIVE 

Charakteristika produktu

Flamazine Cream: 1 June 2010 

1 of 6 

PRODUCT INFORMATION

NAME OF THE MEDICINE: 

FLAMAZINE™ CREAM 1.0% w/w

SILVER SULFADIAZINE 1% W/W 

COMPOSITION
: _Active ingredient_. Silver sulfadiazine.
 _Excipients._ Polysorbate 60 Ph. Eur, 
Polysorbate 80 Ph. Eur, Glyceryl Monostearate Ph. Eur, Cetyl Alcohol
Ph. Eur, Liquid 
Paraffin Ph. Eur, Propylene Glycol Ph. Eur and Purified Water Ph. Eur.

DESCRIPTION:  

A sterile white hydrophilic cream containing silver sulfadiazine 1%.
The cream is a semisolid 
oil-in-water emulsion. The silver sulfadiazine is in a fine
micronised form.   

Silver sulfadiazine is a white or creamy-white, odourless or almost
odourless crystalline 
powder, which becomes yellow on exposure to light.  Practically
insoluble in water; slightly 
soluble in acetone; practically insoluble in alcohol, chloroform or
ether; freely soluble in 
strong ammonia solution.  

Chemical name:  

Silver salt of N’-(pyrimidin-2-yl)sulfanilamide.  C
10
H
9
AgN
4
O
2
S. M.W.  357.1  

CAS 22199-08-2  

Chemical structure: 

PHARMACOLOGY:  

Silver sulfadiazine is a sulfonamide and has broad antimicrobial
activity against both Gram-
positive and Gram-negative organisms.   

Silver sulfadiazine acts on the cell membrane and cell wall. Unlike
sulfadiazine or other 
sulfonamides, the antibacterial action of the silver salt of
sulfadiazine does not appear to 
depend on inhibition of folic acid synthesis. Its action is not
antagonised by p-aminobenzoic 
acid.  

Flamazine Cream: 1 June 2010 

2 of 6 
Microbiology: Silver sulfadiazine has broad antimicrobial activity
against both Gram-positive 
and Gram-negative organisms including _Pseudomonas aeruginosa_, some
yeasts and fungi. 
It has also been reported to be active _in vitro_ against herpes
virus and _Treponema pallidum. _
Sulfonamides act by interfering with the synthesis of nucleic acids
in sensitive micro-
organism