DOXYCYCLINE MONOHYDRATE- doxycycline capsule

Země: Spojené státy

Jazyk: angličtina

Zdroj: NLM (National Library of Medicine)

Aktivní složka:

DOXYCYCLINE (UNII: N12000U13O) (DOXYCYCLINE ANHYDROUS - UNII:334895S862)

Dostupné s:

Physicians Total Care, Inc.

INN (Mezinárodní Name):

DOXYCYCLINE

Složení:

DOXYCYCLINE ANHYDROUS 100 mg

Podání:

ORAL

Druh předpisu:

PRESCRIPTION DRUG

Terapeutické indikace:

To reduce the development of drug-resistant bacteria and maintain effectiveness of Doxycycline Monohydrate Capsules and other antibacterial drugs, Doxycycline Monohydrate Capsules should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Doxycycline is indicated for the treatment of the following infections:     Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae .     Respiratory tract infections caused by Mycoplasma pneumoniae .     Lymphogranuloma venereum caused by Chlamydia trachomatis .     Psittacosis (ornithosis) caused by Chlamydia psittaci .     Trachoma caused by Chlamydia trachomatis , althoug

Přehled produktů:

Doxycycline Monohydrate Capsules 100 mg have an ivory opaque body with a brown opaque cap. The capsule bears the inscription WATSON 411 in white and 100 mg in brown. Each capsule contains doxycycline monohydrate equivalent to 100 mg of doxycycline, supplied in Store at 20° - 25°C (68° -77°F). [See USP controlled room temperature.] Dispense in a tight light-resistant container as defined in the USP/NF.

Stav Autorizace:

New Drug Application Authorized Generic

Charakteristika produktu

DOXYCYCLINE MONOHYDRATE - DOXYCYCLINE CAPSULE
PHYSICIANS TOTAL CARE, INC.
----------
_DOXYCYCLINE MONOHYDRATE CAPSULES_
REVISED: JANUARY 2012
RX ONLY
191157-4
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of Doxycycline
Monohydrate Capsules and other antibacterial drugs, Doxycycline
Monohydrate Capsules should be
used only to treat or prevent infections that are proven or strongly
suspected to be caused by bacteria.
DESCRIPTION
Doxycycline is a broad-spectrum antibiotic synthetically derived from
oxytetracycline. Doxycycline
Monohydrate Capsules 100 mg, 75 mg, and 50 mg contain doxycycline
monohydrate equivalent to 100
mg, 75 mg, or 50 mg of doxycycline for oral administration. The
chemical designation of the light-
yellow crystalline powder is alpha-6-deoxy-5-oxytetracycline.
Structural formula:
C
H N O • H O
M.W. = 462.45
Doxycycline has a high degree of lipid solubility and a low affinity
for calcium binding. It is highly
stable in normal human serum. Doxycycline will not degrade into an
epianhydro form.
Inert ingredients: colloidal silicon dioxide; magnesium stearate;
microcrystalline cellulose; sodium
starch glycolate; and a hard gelatin capsule which contains black iron
oxide, red iron oxide, titanium
dioxide, and yellow iron oxide for the 100 mg and 75 mg strengths,
titanium dioxide and yellow iron
oxide for the 50 mg strength. The capsules are printed with edible ink
containing black iron oxide, red
iron oxide, and yellow iron oxide for the 50 mg and 100 mg strengths
and black iron oxide, FD&C Blue
No. 2, FD&C Red No. 40, FD&C Blue No. 1, and D&C Yellow No. 10 for the
75 mg strength.
CLINICAL PHARMACOLOGY
Tetracyclines are readily absorbed and are bound to plasma proteins in
varying degrees. They are
concentrated by the liver in the bile and excreted in the urine and
feces at high concentrations in a
biologically active form. Doxycycline is virtually completely absorbed
after oral administration.
Following a 200 mg dose of doxycycline monohydrate, 24 normal adult
vo