Země: Izrael
Jazyk: angličtina
Zdroj: Ministry of Health
PETHIDINE HYDROCHLORIDE
TEVA ISRAEL LTD
N02AB02
SOLUTION FOR INJECTION
PETHIDINE HYDROCHLORIDE 50 MG/ML
S.C, I.M, I.V
Required
TEVA ISRAEL LTD, ISRAEL
PETHIDINE
PETHIDINE
Relief of severe pain pre-operative medication support of anesthesia obstetrical analgesia.
2021-08-31
עבט מ"עב תויטבצמרפ תוישעת . הנאתה בוחר 1 הישעת קראפ ן"מח , .ד.ת 975 , םהוש 60850 :לט 6864645 - 03 סקפ , 6864944 - 03 www.tevapharm.com _ _ ילוי 2018 ה/דבכנ ת/חקור ,ה/ אפור , עבט תרבח :ןלהל טרופמכ עדימ ינוכדע לע עידוהל תשקבמ DOLESTINE SOLUTION FOR I.M., I.V. OR S.C. INJECTION ןיטסלוד הקרזהל הסימת רירשה ךותל דירוה ךותל , וא רועל תחתמ _ לש הלופמא לכ_ _1_ _ _ _הליכמ ל"_ _מ_ _ :_ _Pethidine (meperidine) hydrochloride 50 mg_ _ _ _ לש הלופמא לכ_ _2_ _ _ _הליכמ ל"מ_ _ :_ _Pethidine (meperidine) hydrochloride 100 mg_ _ _ _ _ תפסוה "BLACK BOX" םייטאיפואה תצובקמ םירישכת ינולעב --------------------------------------------------------------------------------------------------------------------- יוותה ה :םושירה תדועתב הרשואש יפכ Relief of severe pain, pre-operative medication, support of anesthesia, obstetrical analgesia. לעב תפסותה :ןלהלכ איה ןו WARNING: RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death (see Precautions and Drug Interactions). Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required. Follow patients for signs and symptoms of respiratory depression and sedation. ןולעה ל אפור םוסרפל חלשנ אה רתאבש תופורתה רגאמב י תואירבה דרשמ לש טנרטנ HTTP://WWW.HEALTH.GOV.IL לבקל ןתינו ו עבט תרבחל הינפ י"ע ספדומ . Přečtěte si celý dokument
COMPOSITION _Active Ingredient_ Each ampoule of 1 ml contains: Pethidine (meperidine) hydrochloride 50 mg Each ampoule of 2 ml contains: Pethidine (meperidine) hydrochloride 100 mg _Other Ingredients_ Water for injections, sodium hydroxide (q.s.for pH adjustment). MECHANISM OF ACTION Dolestine is a powerful narcotic analgesic. WARNING: RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death (see Precautions and Drug Interactions). Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required. Follow patients for signs and symptoms of respiratory depression and sedation. INDICATIONS ∙ Relief of severe pain. ∙ Pre-operative medication. ∙ Support of anesthesia. ∙ Obstetrical analgesia. CONTRAINDICATIONS Known hypersensitivity to the preparation. Pethidine is contraindicated in patients who are receiving monoamine oxidase inhibitors, or those who have recently received such agents. Therapeutic doses of pethidine have occasionally precipitated unpredictable, severe, and occasionally fatal reactions in patients who have received monoamine oxidase inhibitors within the last 14 days. The mechanism of these reactions is unclear, but may be related to a pre-existing hyperphenylalaninemia. Some have been characterized by coma, severe respiratory depression, cyanosis and hypotension, and have resembled the syndrome of acute narcotic overdose. In other reactions, the predominant manifestations have been hyperexcitability, convulsions, tachycardia, hyperpyrexia, and hypertension. Although it is not known that other narcotics are free of the risk of such reactions, virtually all of the reported reactions have occurred with pethidine. If a narcotic is needed in such patients, a sensitivity test should be pe Přečtěte si celý dokument