Země: Malajsie
Jazyk: angličtina
Zdroj: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
CHLORPHENIRAMINE MALEATE
ZONTRON PHARMACEUTICALS SDN. BHD.
CHLORPHENIRAMINE MALEATE
60 ml mL; 120ml mL; 100 ml mL
TERAPUTICS SDN BHD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ CHLORITON FORTE SYRUP Chlorpheniramine maleate (4 mg per 5 ml) 1 WHAT IS IN THIS LEAFLET 1. What Chloriton Forte Syrup is used for 2. How Chloriton Forte Syrup it works 3. Before you use Chloriton Forte Syrup 4. How to use Chloriton Forte Syrup 5. While you are using it 6. Side effects 7. Storage and Disposal of Chloriton Forte Syrup 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT CHLORITON FORTE SYRUP IS USED FOR Chloriton Forte Syrup is used to treat symptoms of allergies. HOW CHLORITON FORTE SYRUP WORKS Chloriton Forte Syrup contains, chlorpheniramine maleate, which blocks production of certain natural substance (histamine) that causes allergic reaction. BEFORE YOU USE CHLORITON FORTE SYRUP _- When you must not use it _ Do not take Chloriton Forte Syrup: if you are allergic to chlorpheniramine maleate or any other ingredients of this medicine (listed in Product Description) _Pregnancy and lactation _ Please consult your doctor or pharmacist if you are pregnant, planning for pregnancy or think you may be pregnant. Do not take Chloriton Forte Syrup if you are breast-feeding. You should stop nursing if you need to take the medicine. _- Before you start to use it _ Tell your doctor or pharmacist before taking Chloriton Forte Syrup if: you have urinary related problems such as bladder neck obstruction, enlarged prostate gland, urinary retention etc. you have glaucoma (increased eye pressure) you have asthma you have overactive thyroid you have heart disease you have high blood pressure you have stomach ulcer or intestinal obstruction you have impaired kidney or liver function. Do not give to children less than 6 years without consulting doctor or pharmacist's advice. _- Taking other medicines _ Tell your doctor or pharmacist if you are taking: alcohol medicines that affects neurological function such as maprotiline tricyclic antidepressant (for depressio Přečtěte si celý dokument
PRODUCT LITERATURE CHLORITON FORTE SYRUP 4MG/5ML EACH 5ML CONTAINS Chlorpheniramine Maleate 4 mg Preservatives: Methyl Paraben 0.1% w/v Propyl Paraben 0.01% w/v PRODUCT DESCRIPTION Red coloured clear syrup with sweet taste and fruity odour PHARMACODYNAMICS / PHARMACOKINETICS _MECHANISM OF ACTION/EFFECT: _ Antihistaminic (H 1 -receptor): Antihistamines used in the treatment of allergy act by competing with histamine for H 1 - receptor sites on effector cells. They thereby prevent, but do not reverse, responses mediated by histamine alone. Antihistamines antagonize, in varying degrees, most of the pharmacological effects of histamine, including urticaria and pruritus. Also, the anticholinergic actions of most antihistamines provide a drying effect on the nasal mucosa. Chlorpheniramine is readily absorbed from the GIT after oral administration. Protein binding for Chlorpheniramine is 72%. Onset of action is 15 - 60 minutes after oral administration while time to peak concentration is 2 - 6 hours and time to peak effect is 6 hours after oral administration. It metabolised in the liver and excreted as metabolites via urine within 24 hours. In children Chlorpheniramine have been found to have shorter elimination half-life values. _ _ INDICATION: Anti-histaminic therapy RECOMMENDED DOSE: To be taken 3 to 4 times a day Adult : 5ml (1 teaspoonful) 6 - 12 years : 2.5ml (1/2 teaspoonful Geriatric patients may be more sensitive to the effects of the usual adult dosage. May be taken with food, water or milk to lessen gastric irritation. Not recommended for children under 6 years of age. ROUTE OF ADMINISTRATION Oral CONTRAINDICATIONS: _EXCEPT UNDER SPECIAL CIRCUMSTANCES, THIS MEDICATION SHOULD NOT _ _BE USED WHEN THE FOLLOWING MEDICAL PROBLEMS EXIST: _ - Hepatic and renal function impairment. _RISK-BENEFIT SHOULD BE CONSIDERED WHEN THE FOLLOWING MEDICAL _ _PROBLEMS EXIST: _ -Bladder neck obstruction or symptomatic prostatic hypertrophy or predisposition to urinary retention: anticholinergic effects may precipitate or aggravate Přečtěte si celý dokument