Bexiprost 0.005%wv Eye Drops

Země: Malajsie

Jazyk: angličtina

Zdroj: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktivní složka:

LATANOPROST

Dostupné s:

Vitamode Sdn.bhd

INN (Mezinárodní Name):

LATANOPROST

Jednotky v balení:

2.5 ml

Výrobce:

BEXIMCO PHARMACEUTICAL LTD

Informace pro uživatele

BEXIPROST 0.005%W/V EYE DROPS
Latanoprost 0.05mg
1
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
IN THIS LEAFLET:
1.
What Bexiprost Eye Drops is used
for
2.
How Bexiprost Eye Drops work
3.
Before you use Bexiprost Eye Drops
4.
How to use Bexiprost Eye Drops
5.
While you are using Bexiprost Eye
Drops
6.
Side effects
7.
Storage and Disposal Bexiprost Eye
Drops
8.
Product description
9.
Manufacturer and Product
Registration Holder
10.
Date of Revision
WHAT
Bexiprost EYE DROPS IS USED FOR
Bexiprost Eye Drops are used for the
reduction of eye pressure in patients with
open-angle
glaucoma,
chronic
angle
closure glaucoma or ocular hypertension.
These
conditions
are
linked
with
an
increase in the pressure within the eyes,
eventually
affecting
the
eye
sight.
Bexiprost
Eye
drops
are
also
used
in
reduction
of
increase
eye
pressure
in
children.
HOW
Bexiprost EYE DROPS WORK
Latanoprost
works
by
reduction
of
elevated intraocular pressure within the
eyes by increasing the natural outflow of
fluid from inside the eye into the blood
stream.
BEFORE YOU USE
Bexiprost EYE DROPS
-
_When you must not use it _
Do not use Bexiprost Eye Drops, if you
are
allergic
to
either
Latanoprost
benzalkonium
chloride
or
any
of
the
other ingredients in this medicine
-
_Pregnancy and Lactation _
Do not use Bexiprost Eye Drops if you
are pregnant, trying to get pregnant or
think you may be pregnant.
Do not use Bexiprost Eye Drops if you
are breast-feeding. Ask your doctor or
pharmacist for advice before taking any
medicine.
-
_Before you start to use it _
Before using your medicine, consult your
doctor or pharmacist if:
•
if you have any kind of eye
condition
•
if you are undergoing cataract
surgery
•
if you have history of viral infection
of the eyes
•
if you have asthma
•
if you have inflammation of eyes
•
If you wear contact lenses, you
should remove them before using
Bexiprost. After using Bexiprost
you should wait 15 minutes before
putting your contact lenses back in
-
_Taking other medicines _
Tell your doctor if you are taking a

Charakteristika produktu

Bexiprost
0.005% w/v Eye Drops
Latanoprost 0.05mg
Description
Colourless or pale yellow, clear solution.
Pharmacodynamics
Pharmacotherapeutic group: Antiglaucoma preparations and miotics,
prostaglandin analogues ATC code:
S01EE01
The active substance latanoprost, a prostaglandin F
2α
analogue, is a selective prostanoid FP receptor
agonist which reduces the intraocular pressure by increasing the
outflow of aqueous humour. Reduction
of the intraocular pressure in man starts about three to four hours
after administration and maximum
effect is reached after eight to twelve hours. Pressure reduction is
maintained for at least 24 hours.
The main mechanism of action is increased uveoscleral outflow,
although some increase in outflow
facility (decrease in outflow resistance) has been reported in man.
Latanoprost is effective as monotherapy. In addition, latanoprost is
effective in combination with beta-
adrenergic antagonists (timolol). The effect of latanoprost is
additive in combination with adrenergic
agonists (dipivalyl epinephrine), oral carbonic anhydrase inhibitors
(acetazolamide) and at least partly
additive with cholinergic agonists (pilocarpine).
Latanoprost has no significant effect on the production of aqueous
humour. Latanoprost has not been
found to have any effect on the blood-aqueous barrier.
Latanoprost has no or negligible effects on the intraocular blood
circulation. However, mild to moderate
conjunctival or episcleral hyperaemia may occur during topical
treatment.
Latanoprost has not induced fluorescein leakage in the posterior
segment of pseudophakic human eyes
during short-term treatment.
Latanoprost in clinical doses has not been found to have any
significant pharmacological effects on the
cardiovascular or respiratory system.
Pharmacokinetics
Latanoprost (mw 432.58) is an isopropyl ester prodrug which per se is
inactive, but after hydrolysis to the
acid of latanoprost becomes biologically active.
The prodrug is well absorbed through the cornea and all drug that
enters the aqueous humour is
hydrol