Estats Units - anglès - NLM (National Library of Medicine)

glaxosmithkline llc - mupirocin calcium (unii: rg38i2p540) (mupirocin - unii:d0gx863oa5) - mupirocin 20 mg in 1 g - bactroban nasal ointment is indicated for the eradication of nasal colonization with methicillin‑resistant staphylococcus aureus (mrsa) in adult and pediatric patients (aged 12 years and older) and healthcare workers as part of a comprehensive infection control program to reduce the risk of infection among patients at high risk of mrsa infection during institutional outbreaks of infections with this microorganism. bactroban nasal ointment is contraindicated in patients with known hypersensitivity to mupirocin or any of the excipients of bactroban nasal ointment. risk summary there are insufficient human data to establish whether there is a drug-associated risk with bactroban nasal ointment in pregnant women. mupirocin absorption was negligible following repeated intranasal administration of bactroban nasal ointment [see clinical pharmacology 12.3)] , but the dose regimen used in this study did not mimic recommended clinical use. no developmental toxicity was observed in rats or rabbits treated with mupirocin

Estats Units - anglès - NLM (National Library of Medicine)

glaxosmithkline llc - vardenafil hydrochloride (unii: 5m8s2cu0ts) (vardenafil - unii:uce6f4125h) - vardenafil 11.85 mg - staxyn® is indicated for the treatment of erectile dysfunction. administration of staxyn with nitrates (either regularly and/or intermittently) and nitric oxide donors is contraindicated [see clinical pharmacology (12.2)] . consistent with the effects of pde5 inhibition on the nitric oxide/cyclic guanosine monophosphate pathway, pde5 inhibitors, including staxyn, may potentiate the hypotensive effects of nitrates. a suitable time interval following staxyn dosing for the safe administration of nitrates or nitric oxide donors has not been determined. do not use staxyn in patients who are using a gc stimulator, such as riociguat. pde5 inhibitors, including staxyn may potentiate the hypotensive effects of gc stimulators. staxyn is not indicated for use in females. there are no data with the use of staxyn in pregnant women to inform any drug-associated risks. in animal reproduction studies conducted in pregnant rats and rabbits, no adverse developmental outcomes were observed with oral administration of vardenafi

Estats Units - anglès - NLM (National Library of Medicine)

glaxosmithkline llc - fluticasone furoate (unii: js86977wnv) (fluticasone - unii:cut2w21n7u) - fluticasone furoate 27.5 ug - veramyst® (fluticasone furoate) nasal spray is indicated for the treatment of the symptoms of seasonal and perennial allergic rhinitis in patients aged 2 years and older. veramyst nasal spray is contraindicated in patients with hypersensitivity to any of its ingredients [see warnings and precautions (5.3)] . teratogenic effects pregnancy category c. corticosteroids have been shown to be teratogenic in laboratory animals when administered systemically at relatively low dosage levels. there were no teratogenic effects in rats and rabbits at inhaled fluticasone furoate dosages of up to 91 and 8 mcg/kg/day, respectively (approximately 7 and 1 times, respectively, the maximum recommended daily intranasal dose in adults on a mcg/m2 basis). there was also no effect on pre- or post-natal development in rats treated with up to 27 mcg/kg/day by inhalation during gestation and lactation (approximately 2 times the maximum recommended daily intranasal dose in adults on a mcg/m2 basis). there are no adequate and well-co

Estats Units - anglès - NLM (National Library of Medicine)

glaxosmithkline llc - mupirocin calcium (unii: rg38i2p540) (mupirocin - unii:d0gx863oa5) - mupirocin 20 mg in 1 g - bactroban cream is indicated for the treatment of secondarily infected traumatic skin lesions (up to 10 cm in length or 100 cm2 in area) due to susceptible isolates of staphylococcus aureus (s. aureus) and streptococcus pyogenes (s. pyogenes) . bactroban cream is contraindicated in patients with known hypersensitivity to mupirocin or any of the excipients of bactroban cream. risk summary there are insufficient human data to establish whether there is a drug-associated risk with bactroban cream in pregnant women. systemic absorption of mupirocin through intact human skin is minimal following topical administration of bacroban cream [see clinical pharmacology (12.3)] . no developmental toxicity was observed in rats or rabbits treated with mupirocin subcutaneously during organogenesis at doses of 160 or 40 mg per kg per day, respectively (22 and 11 times the human topical dose based on calculations of dose divided by the entire body surface area). the estimated background risk of major birth defects and miscar

Estats Units - anglès - NLM (National Library of Medicine)

glaxosmithkline llc - nelarabine (unii: 60158cv180) (nelarabine - unii:60158cv180) - nelarabine 5 mg in 1 ml

Estats Units - anglès - NLM (National Library of Medicine)

glaxosmithkline llc - ranitidine hydrochloride (unii: bk76465ihm) (ranitidine - unii:884kt10yb7) - ranitidine 150 mg

Estats Units - anglès - NLM (National Library of Medicine)

glaxosmithkline llc - ondansetron hydrochloride (unii: nmh84ozk2b) (ondansetron - unii:4af302esos) - ondansetron 2 mg in 1 ml

Estats Units - anglès - NLM (National Library of Medicine)

glaxosmithkline llc - argatroban (unii: iy90u61z3s) (argatroban anhydrous - unii:ocy3u280y3) - argatroban 100 mg in 1 ml

Estats Units - anglès - NLM (National Library of Medicine)

glaxosmithkline llc - salmeterol xinafoate (unii: 6ew8q962a5) (salmeterol - unii:2i4bc502bt) - salmeterol 50 ug

Estats Units - anglès - NLM (National Library of Medicine)

glaxosmithkline llc - dutasteride (unii: o0j6xjn02i) (dutasteride - unii:o0j6xjn02i) -