PAMOL TABLET

País: Malàisia

Idioma: anglès

Font: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

ingredients actius:

Paracetamol

Disponible des:

SUNWARD PHARMACEUTICAL SDN. BHD.

Designació comuna internacional (DCI):

Paracetamol

Unidades en paquete:

1000 Tablets; 500 Tablets; 100 Tablets; 2500 Tablets; 240 Tablets; 1000 Tablets; 50 Tablets

Fabricat per:

SUNWARD PHARMACEUTICAL SDN. BHD.

Informació per a l'usuari

PAMOL TABLET / PAMOL 650 TABLET
Paracetamol (500mg, 650mg)
1
_ CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET
1. What Pamol Tablet is used for
2. How Pamol Tablet works
3. Before you use Pamol Tablet
4. How to Pamol Tablet
5. While you are using it
6. Side effects
7. Storage and disposal of Pamol Tablet
8. Product description
9. Manufacturer and Product Registration
Holder
10.Date of revision
WHAT PAMOL TABLET IS USED FOR
It is used for relief discomfort and fever
such as the common cold and viral infections.
It also help to relief musculoskeletal pain as
well as in other painful disorders such as
headaches,
dysmenorrhea
(period
paid
or
abdominal
cramp,
muscle
weakness
and
severe pain due to nerve intense or damage.
HOW PAMOL TABLET WORKS
The
active
ingredient
in
the
medicine
is
Paracetamol. Paracetamol has analgesic and
antipyretic
mechanism
to
reduce
anti-
inflammatory action to relief pain and reduc-
ing fever.
BEFORE YOU USE PAMOL TABLET
_- When you must not use it _
Do not take this medicine if you

are hypersensitive to paracetamol or any of
the other ingredients listed at the end of the
leaflet.
_ _

have liver damage.
_ _

concominat
administration
of
other
medicine that contains paracetamol at same
time.
_ _
_- Before you start to use it _
Tell your doctor before taking this medicine
if you have:

liver and kidney problem.
_Pregnancy and breastfeeding _
You should check with your doctor if you are
or think you may be pregnant, planning to
become pregnant or if you are breastfeeding.
It is not recommended for pregnant women
and
nursing
mothers
unless
the
expected
benefit outweighs any potential risks.
There
is
inadequate
evidence
of
safety
in
human pregnancy. Safety during pregnancy
has not been established. Caution should be
taken when breastfeeding.
_- Taking other medicines _
There are a few medicines which may interact
with Pamol Tablet. It is important to tell your
doctor or pharmacist about all the medicines
that you are taking, including those obtained
without

Fitxa tècnica

PHARMACOLOGY:
Paracetamol produces anti-pyresis through action on the hypothalamic
heat-regulating
center and analgesia by elevation of the pain threshold. Paracetamol
is readily absorbed
from the gastrointestinal tract with peak plasma concentration
occurring about 30 minutes
to 2 hours after ingestion. It is metabolised in the liver and
excreted in the urine as the
glucuronide
and
sulphate
conjugates.
Less
than
5%
is
excreted
as
unchanged
Paracetamol. The elimination half life varies from about 1 to 4 hours.
Plasma protein
binding is negligible at usual therapeutic concentrations but
increases with increasing
concentrations. It is reported that the binding of paracetamol to
plasma protein did not
occur with plasma concentration of less than 60mcg per ml,
corresponding to the usual
therapeutic concentration. After toxic doses of paracetamol, up to 43%
could be bound to
plasma proteins.
INDICATIONS:
It is indicated as an analgesic and antipyretic in diseases
accompanied by discomfort and
fever such as the common cold and other viral infections. It also
provides analgesia in
conditions involving musculoskeletal pain as well as in other painful
disorders such as
headaches, dysmenorrhoea, myalgia and neuralgia.
CONTRAINDICATIONS:
It is contraindicated in patients who are hypersensitive to it and
also in patients who have
liver impairment.
SIDE EFFECTS/ADVERSE REACTIONS:
Side-effects of paracetamol are usually mild, though haematological
reactions such as
agranulocytosis, thrombocytopenia and pancytopenia have been reported.
Cutaneous
hypersensitivity
reactions
including
skin
rashes,
angioderma,
Stevens
Johnson
Syndrome/Toxic Epidermal Necrolysis have been reported.
PRECAUTIONS/WARNINGS:
Paracetamol should be given with care to patients with impaired kidney
or liver function.
Paracetamol could interfere with paper chromatographic estimations of
urinary amino
acids by producing drug spots, and could interfere technically with
laboratory estimations
for metadrenalines in the urine to produce erroneous raised results.
P