País: Regne Unit
Idioma: anglès
Font: MHRA (Medicines & Healthcare Products Regulatory Agency)
Amiloride hydrochloride; Furosemide
Milpharm Ltd
C03EB01
Amiloride hydrochloride; Furosemide
2.5mg ; 20mg
Oral tablet
Oral
No Controlled Drug Status
Valid as a prescribable product
BNF: 02020400; GTIN: 8901175710119
PACKAGE LEAFLET: INFORMATION FOR THE USER CO-AMILOFRUSE 2.5/20MG TABLETS CO-AMILOFRUSE 5/40MG TABLETS CO-AMILOFRUSE 10/80MG TABLETS (amiloride hydrochloride and furosemide) READ ALL OF THIS LEAET CAREFULLY BEFORE YOU START TAKING THIS MEDICINE BECAUSE IT CONTAINS IMPORTANT INFORMATION FOR YOU. • Keep this leaet. You may need to read it again. • If you have any further questions, ask your doctor or pharmacist. • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaet. See section 4. WHAT IS IN THIS LEAET: 1. What Co-Amilofruse Tablets are and what are they used for 2. What you need to know before you take Co-Amilofruse Tablets 3. How to take Co-Amilofruse Tablets 4. Possible side effects 5. How to store Co-Amilofruse Tablets 6. Contents of the pack and other information Co-Amilofruse Tablets contain the active ingredients: • furosemide, belonging to a group of medicines called loop diuretics which remove excess water but can cause a loss of potassium from the body. • amiloride hydrochloride belongs to a group of medicines known as potassium sparing diuretics which also remove excess water but prevent excessive loss of potassium from the body. Co-Amilofruse Tablets are prescribed for adults only for the treatment of heart failure, kidney problems, or uid retention due to steroids, oestrogens or cirrhosis of the liver. DO NOT TAKE CO-AMILOFRUSE TABLETS IF YOU: • have an allergy (hypersensitivity) to any of the ingredients in the product (_see Section 6 and end of _ _Section 2_) Signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue. • have kidney failure • have a low blood volume or are dehydrated • have high blood potassium levels or any disturbance of other blood electrolytes (salts) which Llegiu el document complet
OBJECT 1 CO-AMILOFRUSE 20/2.5MG TABLETS Summary of Product Characteristics Updated 26-Jul-2017 | Aurobindo Pharma - Milpharm Ltd. 1. Name of the medicinal product Co-Amilofruse 2.5/20mg Tablets 2. Qualitative and quantitative composition Each tablet contains 2.5mg of Amiloride Hydrochloride (dihydrate) and 20mg of Furosemide. For a full list of excipients, see section 6. 1. 3. Pharmaceutical form Tablets for oral use. Pale orange circular, flat faced beveled edge tablets, debossed with ARD | 20 on one side and plain on the other side. 4. Clinical particulars 4.1 Therapeutic indications Co-Amilofruse is a potassium sparing diuretic which is indicated where a prompt diuresis is required. It is of particular value in conditions where potassium conservation is important: congestive cardiac failure, nephrosis, fluid retention due to corticosteroid or oestrogen therapy and ascites associated with cirrhosis. 4.2 Posology and method of administration The starting dose is usually 5/40mg, subsequent dosage being adjusted to suit the needs of the patient. _Adults:_ One to two tablets to be taken in the morning. _Children:_ Not recommended for children under 18 years of age as safety and efficacy have not been established. _Elderly:_ The dosage should be adjusted according to diuretic response. Serum electrolytes and urea should be carefully monitored. 4.3 Contraindications Patients with hypovolaemia or dehydration (with or without accompanying hypotension). Patients with an impaired renal function and a creatinine clearance below 30ml/min per 1.73 m 2 body surface area, anuria or renal failure with anuria not responding to furosemide, renal failure as a result of poisoning by nephrotoxic or hepatotoxic agents or renal failure associated with hepatic coma, severe hypokalaemia, severe hyponatraemia, hyperkalaemia (serum potassium > 5.3 mmol/llitre), addison's disease, precomatose states associated with cirrhosis, concomitant potassium supplements or potassium sparing diuretics, electrolyte imbalance and breast feeding women. Llegiu el document complet