CITANEST 3% WITH OCTAPRESSIN 1.8mL injection cartridge

País: Austràlia

Idioma: anglès

Font: Department of Health (Therapeutic Goods Administration)

ingredients actius:

prilocaine hydrochloride, Quantity: 30 mg/mL; felypressin, Quantity: 0.03 IU/mL

Disponible des:

Dentsply Sirona Pty Ltd

Designació comuna internacional (DCI):

Felypressin,Prilocaine hydrochloride

formulario farmacéutico:

Injection, solution

Composición:

Excipient Ingredients: sodium chloride; water for injections; hydrochloric acid; sodium hydroxide; sodium acetate; chlorobutanol hemihydrate; acetic acid

Vía de administración:

Intramuscular, Subcutaneous, Infiltration

Unidades en paquete:

1.8 mL x 100

tipo de receta:

(S4) Prescription Only Medicine

indicaciones terapéuticas:

INDICATIONS AS AT 23 JULY 2003 : CITANEST is indicated for the production of local anaesthesia in routine dental procedures and oral surgery by means of infiltration and nerve block tecniques.

Resumen del producto:

Visual Identification: Clear colourless particle-free solution; Container Type: Cartridge; Container Material: Glass Type I Clear; Container Life Time: 2 Years; Container Temperature: Store below 25 degrees Celsius

Estat d'Autorització:

Registered

Data d'autorització:

2008-05-21

Informació per a l'usuari

CITANEST
® DENTAL WITH
OCTAPRESSIN
®
_Prilocaine Hydrochloride with Felypressin _
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Citanest DENTAL
with Octapressin.
It does not contain all the available
information. It does not take the place
of talking to your dental practitioner or
dental nurse.
All medicines have risks and benefits.
Your dental practitioner has weighed
the risks of you using this medicine
against the benefits they expect it will
have for you.
IF YOU HAVE ANY CONCERNS ABOUT
BEING GIVEN THIS MEDICINE, ASK YOUR
DENTAL PRACTITIONER.
KEEP THIS LEAFLET.
You may need to read it again.
WHAT CITANEST DENTAL
WITH OCTAPRESSIN IS USED
FOR
Citanest DENTAL with Octapressin is
used to prevent or relieve pain during
dental procedures, but it will not put
you to sleep.This medicine belongs to a
group of medicines called local
anaesthetics.
It is injected into the gums and works
by making the nerves unable to pass
pain messages to the brain.
Depending on the amount used, it will
either totally stop pain or will cause a
partial loss of feeling.
The felypressin makes the blood
vessels at the site of injection narrower,
which means you bleed less. It is then
easier for your dental practitioner to
see what is happening.
ASK YOUR DENTAL PRACTITIONER IF YOU
HAVE ANY QUESTIONS ABOUT WHY THIS
MEDICINE HAS BEEN PRESCRIBED FOR
YOU.
This medicine is not addictive.
BEFORE YOU ARE GIVEN
CITANEST DENTAL WITH
OCTAPRESSIN
_WHEN YOU MUST NOT BE GIVEN _
_IT _
DO NOT TAKE CITANEST DENTAL WITH
OCTAPRESSIN IF YOU HAVE AN ALLERGY
TO:
•
any medicine containing
prilocaine
•
any of the ingredients listed at
the end of this leaflet
•
any other similar medicines,
such as other local anaesthetics
e.g. Xylocaine.
Some of the symptoms of an allergic
reaction may include
•
shortness of breath
•
wheezing or difficulty breathing
•
swelling of the face, lips, tongue
or other parts of the body
•
rash, itching or hives on the
skin.
DO NOT TAKE CITANEST DENTAL WITH
OCTAPRESSIN I

Fitxa tècnica

3% CITANEST
® DENTAL WITH OCTAPRESSIN
®
PRODUCT INFORMATION
NAME OF THE MEDICINE
3% Citanest
®
Dental with Octapressin
®
contains prilocaine hydrochloride and
felypressin as the active substances.
The chemical structure of prilocaine hydrochloride is:
The structure of felypressin is:
Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-GlyNH
2
DESCRIPTION
3% Citanest Dental with Octapressin is a sterile isotonic aqueous
solution. Excipients:
sodium chloride and water for injections and may also contain sodium
hydroxide and/or
hydrochloric acid for pH adjustment to 3.5-5.2.
The chemical name of prilocaine hydrochloride is
2-(propylamino)-o-propionotoluidide
hydrochloride; and it is also known as propitocaine hydrochloride. It
has a molecular
weight of 256.8. The CAS number of prilocaine hydrochloride is
1786-81-8.
The chemical name of the vasoconstrictor octapressin is
2-(phenylalanine)-8-lysine
vasopressin; also known as felypressin. It has a molecular weight of
1040.2. The CAS
number for octapressin is 56-59-7.
PHARMACOLOGY
Prilocaine is a membrane stabilising agent and a local anaesthetic of
the amide type.
Prilocaine stabilises the neuronal membrane and reversibly prevents
the initiation and
conduction of nerve impulses thereby producing local anaesthesia.
Prilocaine has a similar time of onset and potency to lignocaine.
Prilocaine has a lower
toxicity than lignocaine.
The onset and duration of anaesthesia depend on the route of
administration, status of
the patient and the dosage (volume and concentration) employed. The
addition of
felypressin reduces the rate of absorption of prilocaine from the site
of injection thereby
increasing its duration of action.
Felypressin is a synthetic hormone with similar properties to
vasopressin. In contrast to
adrenaline, felypressin does not produce ischaemia distal to or at the
injection site. 3%
Citanest Dental with Octapressin is therefore indicated for routine
use. It is particularly
suitable for use in patients for whom the use of solutions containing
sympathomimetic
agents is contrain