País: Nova Zelanda
Idioma: anglès
Font: Medsafe (Medicines Safety Authority)
Amlodipine besilate 13.88mg equivalent to 10 mg Amlodipine;
Actavis New Zealand Limited
Amlodipine besilate 13.88 mg (equivalent to 10 mg Amlodipine)
10 mg
Tablet
Active: Amlodipine besilate 13.88mg equivalent to 10 mg Amlodipine Excipient: Calcium hydrogen phosphate dihydrate Colloidal silicon dioxide Magnesium stearate Microcrystalline cellulose Sodium starch glycolate
Blister pack, PVC/PVDC, 28 tablets
Prescription
Prescription
Dr Reddy's Laboratories Limited
Amlodipine is indicated for the first line treatment of hypertension and can be used as the sole agent to control blood pressure in the majority of patients. Patients not adequately controlled on a single antihypertensive agent may benefit from the addition of amlodipine, which has been used in combination with a thiazide diuretic, beta adrenoceptor blocking agent, or an angiotensin-converting enzyme inhibitor.
Package - Contents - Shelf Life: Blister pack, PVC/PVDC - 28 tablets - 24 months from date of manufacture stored at or below 25°C - Blister pack, PVC/PVDC - 56 tablets - 24 months from date of manufacture stored at or below 25°C - Blister pack, PVC/PVDC - 84 tablets - 24 months from date of manufacture stored at or below 25°C - Bottle, plastic, HDPE - 100 tablets - 24 months from date of manufacture stored at or below 25°C - Bottle, plastic, HDPE - 250 tablets - 24 months from date of manufacture stored at or below 25°C - Bottle, plastic, HDPE - 500 tablets - 24 months from date of manufacture stored at or below 25°C
2010-04-26
DATA SHEET ARROW - AMLO 5 & ARROW - AMLO 10 Amlodipine besilate 5 mg & 10 mg Tablets PRESENTATION Arrow-Amlo 5 (5 mg tablets) are white to off white, round, biconvex, uncoated tablets. Arrow-Amlo 10 (10 mg tablets) are white to off white, round, biconvex, uncoated tablets. In addition to amlodipine besylate, each tablet contains the following inactive ingredients: Calcium hydrogen phosphate dihydrate Microcrystalline cellulose Silica colloidal anhydrous Sodium starch glycollate Magnesium stearate USES ACTIONS Amlodipine is a calcium ion influx inhibitor (slow channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac and smooth muscle. The mechanism of the antihypertensive action of amlodipine is due to a direct relaxant effect on vascular smooth muscle. The precise mechanism by which amlodipine relieves angina has not been fully determined but amlodipine reduces total ischaemic burden by the following two actions: Amlodipine dilates peripheral arterioles and thus reduces the total peripheral resistance (afterload) against which the heart works. Since the heart rate remains stable, this unloading of the heart reduces myocardial energy consumption and oxygen requirements. The mechanism of action of amlodipine also probably involves dilatation of the main coronary arteries and coronary arterioles, both in normal and ischaemic regions. This dilatation increases myocardial oxygen delivery in patients with coronary artery spasm (Prinzmetal's or variant angina) and blunts Llegiu el document complet