AMOXIL amoxicillin 1g (as sodium) powder for injection vial

País: Austràlia

Idioma: anglès

Font: Department of Health (Therapeutic Goods Administration)

ingredients actius:

amoxicillin sodium, Quantity: 1.06 g (Equivalent: amoxicillin, Qty 1 g)

Disponible des:

Aspen Pharmacare Australia Pty Ltd

formulario farmacéutico:

Injection, powder for

Composición:

Excipient Ingredients:

Vía de administración:

Intramuscular, Intravenous

Unidades en paquete:

10x1g

clase:

Medicine Registered

tipo de receta:

(S4) Prescription Only Medicine

indicaciones terapéuticas:

Amoxil Parenteral is intended for use where the patient's condition precludes the administration of the oral form. It is indicated for the treatment of the following infections due to susceptible strains of sensitive organisms: Note: Therapy should be guided by bacteriological studies, including sensitivity tests, and clinical response. However, in emergency cases where the causative organism has not been identified, therapy with amoxycillin may be useful. Clinical judgement will decide whether combination with another antibiotic would provide a sufficiently broad spectrum of activity pending sensitivity test results. Septicaemia: (bacterial) H. influenzae; E. coli (see Microbiology); P.mirabilis; streptococcus; S. pneumoniae; S. faecalis and Salmonella typhi. Skin and Skin Structure: staphylococcus, non-penicillinase-producing; streptococcus; E. Coli (see Microbiology). Respiratory, Acute and Chronic: Haemophilus influenzae; streptococcus; S. pneumoniae; staphylococcus, non-penicillinase producing; E. co

Resumen del producto:

Visual Identification: A fine white powder; Container Type: Vial; Container Life Time: 2 Years; Container Temperature: Store below 25 degrees Celsius

Estat d'Autorització:

Registered

Data d'autorització:

1991-08-14

Informació per a l'usuari

1
AMOXIL
®
PARENTERAL PREPARATIONS
_Amoxycillin _
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET?
Please read this leaflet carefully
before you use AMOXIL.
This leaflet answers some
common questions about
AMOXIL. It does not contain all
of the available information.
It does not take the place of
talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Sometimes new risks
are found even when a medicine
has been used for many years.
Your doctor has weighed the
expected benefits of you taking
AMOXIL against the risks this
medicine could have for you.
If you have any concerns about
taking this medicine, ask your
doctor or pharmacist.
Keep this leaflet with the
medicine.
You may need to read it again.
WHAT IS AMOXIL USED
FOR?
AMOXIL contains a penicillin
called amoxycillin as the active
ingredient.
Amoxycillin belongs to the
penicillin group of antibiotics.
AMOXIL is used to treat a range
of infections caused by bacteria.
These may be infections of the
blood (septicaemia), chest
(pneumonia), urinary and genital
tract, skin and fleshy tissues.
AMOXIL works by killing the
bacteria that cause these
infections. AMOXIL can also be
used to prevent infection.
Your doctor may have prescribed
AMOXIL for another reason.
There is no evidence that AMOXIL
is addictive.
BEFORE YOU ARE GIVEN
AMOXIL
_ _
_AMOXIL MUST NOT BE USED _
_IF: _

you are allergic to amoxycillin,
other penicillins or similar
types of antibiotics such as
cephalosporins. If you have
ever had an allergic reaction
(such as a rash) when taking
an antibiotic you should tell
your doctor before you take
AMOXIL.

the expiry date (EXP) printed
on the pack has passed.

the packaging is torn or shows
signs of tampering
_TELL YOUR DOCTOR IF: _
You must tell your doctor if:

you are allergic to foods, dyes,
preservatives or any other
medicines.

you have ever had an allergic
reaction (such as a rash) to
any antibiotics in the past.

you have glandular fever
(mononucleosis).

you are pregnant or think you
may be pregnant or ar

Fitxa tècnica

1
PRODUCT INFORMATION
AMOXIL
® PARENTERAL
NAME OF THE MEDICINE
Amoxicillin sodium is a semisynthetic antibiotic and is a member of
the penicillinase-stable group of
penicillins derived from the penicillin nucleus, 6-aminopenicillanic
acid, isolated at Beecham
Research Laboratories. It is identified chemically as sodium
(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-
hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate.
The molecular weight of amoxicillin sodium is 387.4. Amoxicillin
sodium may be represented
structurally as:_ _
_ _
CAS – 61336-70-7.
_ _
DESCRIPTION
Amoxicillin sodium is a white or almost white powder, very
hygroscopic, very soluble in water,
sparingly soluble in ethanol, very slightly soluble in acetone.
PHARMACOLOGY
MICROBIOLOGY
Amoxicillin is similar to ampicillin in its bactericidal action
against Gram-positive and Gram-
negative susceptible organisms during the stage of active
multiplication. It acts through the
inhibition of biosynthesis of the cell wall mucopeptide.
Amoxicillin
is
active_ _
_in _
_vitro_
against
most
strains
of
_Haemophilus _
_influenzae*, _
_Neisseria _
_gonorrhoeae*, _
_Neisseria _
_meningitidis, _
_Escherichia _
_coli*, _
_Proteus _
_mirabilis* _
_and _
Salmonellae.
Because
amoxicillin
does
not
resist
destruction
by
penicillinase,
it
is
not
active
against
penicillinase-producing organisms, particularly
penicillinase-producing staphylococci. All strains of
_Pseudomonas species_, _Klebsiella_ species, _Enterobacter _species,
indole-positive _Proteus_ species,
_Serratia _
_marcescens_,
_Citrobacter _
species,
penicillinase-producing
_N. _
_gonorrhoeae_
and
penicillinase-producing _ H. influenzae_ are resistant. _ In vitro_
studies have demonstrated the
susceptibility of most strains of the following gram-positive
bacteria: alpha- and beta-haemolytic
streptococci,
_Diplococcus _
_pneumoniae_,
non-penicillinase
producing
staphylococci
and
_Streptococcus faecalis. _These organisms_ _are susceptible to
amoxicillin at serum concentrations,
2
which