Zimstat

দেশ: অস্ট্রেলিয়া

ভাষা: ইংরেজি

সূত্র: Department of Health (Therapeutic Goods Administration)

সক্রিয় উপাদান:

Simvastatin

থেকে পাওয়া:

Alphapharm Pty Ltd

শ্রেণী:

Medicine Registered

তথ্য লিফলেট

ZIMSTAT

_contains the active ingredient simvastatin_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Zimstat.
It does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have benefits and
risks. Your doctor has weighed the
risks of you taking Zimstat against
the benefits they expect it will have
for you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, TALK TO YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH YOUR
MEDICINE.
You may need to read it again.
WHAT ZIMSTAT IS USED
FOR
Zimstat helps to reduce the amount
of cholesterol and triglyceride in the
blood.
Everyone has cholesterol and
triglyceride in their blood. They are
types of blood fat needed by the body
for many things, such as building cell
walls, making bile acids (which help
to digest food) and some hormones.
However, too much cholesterol and
triglyceride can be a problem.
Cholesterol is present in many foods
and is also made in your body by the
liver. If your body does not balance
the amount of cholesterol it needs
with the amount of cholesterol eaten,
then your cholesterol becomes too
high.
High cholesterol is more likely to
occur with certain diseases or if you
have a family history of high
cholesterol.
When you have high levels of
cholesterol it may 'stick' to the inside
of your blood vessels instead of
being carried to the parts of the body
where it is needed. Over time, this
can form hard areas (called plaques)
on the walls of your blood vessels,
making it more difficult for the blood
to flow. This blocking of your blood
vessels can lead to heart disease
(such as heart attack and angina) and
stroke.
In patients with coronary heart
disease (CHD) accompanied by high
cholesterol levels, Zimstat may slow
down the hardening of blood vessels
and reduce the risk of new plaque
formation.
If you have CHD, your doctor has
prescribed Zimstat to help prolong
your life and lessen the risk of heart
attack or preven

পণ্য বৈশিষ্ট্য

ZIMSTAT 
_Simvastatin _
PRODUCT INFORMATION 
NAME OF THE MEDICINE 
Active ingredient: 
Simvastatin 
Chemical name: 
[1S-[1  α,  3  α,  7  β,  8  β  (2S*,  4S*),8a  β]]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-
(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl2,2-
dimethylbutanoate. 
Structural formula: 
O
O
H
3
C
H
3
C
CH
3
H
HO
CH
3
H
3
C
H
O
O

Molecular formula:  
C
25
H
38
O
5

Molecular weight:  
418.57 

CAS Registry no.:  
79902-63-9 
DESCRIPTION 
Simvastatin  is  a  white  crystalline  powder,  practically  insoluble  in  water  and  freely  soluble  in  chloroform, 
methanol and ethanol. 
Each tablet for oral administration contains either 5 mg, 10 mg, 20 mg, 40 mg or 80 mg of simvastatin and the 
following  non-medicinal  ingredients:  butylated  hydroxyanisole,  ascorbic  acid,  citric  acid  monohydrate, 
cellulose - microcrystalline, starch - pregelatinised maize, magnesium stearate, hypromellose, lactose, titanium 
dioxide, glycerol triacetate and purified talc.  Iron oxide yellow (CI77492) is a constituent of Zimstat 5 mg, 20 
mg and 40 mg tablets and iron oxide red
(CI77491) of Zimstat 10 mg, 20 mg, 40 mg and 80 mg tablets.  The 40 
mg tablet contains polydextrose, macrogol 8000, iron oxide
yellow (CI77492) and iron oxide red (CI77491). 
PHARMACOLOGY 
CLINICAL PHARMACOLOGY 
The involvement of low-density lipoprotein-cholesterol (LDL-C) in atherogenesis has been well documented in 
clinical  and  pathological  studies,  as  well  as  in  many  animal  experiments.  Epidemiological  studies  have 
established  that  high  LDL-C  and  low  high-density  lipoprotein-cholesterol  (HDL-C)  are  both  risk  factors  for 
coronary heart disease (CHD).  
ZIMSTAT 
– Product Information 
2 

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