দেশ: অস্ট্রেলিয়া
ভাষা: ইংরেজি
সূত্র: Department of Health (Therapeutic Goods Administration)
timolol maleate, Quantity: 6.8 mg/mL (Equivalent: timolol, Qty 5 mg/mL)
Micro Labs Pty Ltd
Eye Drops, solution
Excipient Ingredients: monobasic sodium phosphate dihydrate; sodium hydroxide; dibasic sodium phosphate dodecahydrate; benzalkonium chloride; water for injections
Ophthalmic
5 mL
(S4) Prescription Only Medicine
Timolol ophthalmic solution is indicated for the reduction of elevated intraocular pressure.,In clinical trials it has been shown to reduce intraocular pressure in:,Patients with ocular hypertension,Patients with chronic open-angle glaucoma,Aphakic patients with glaucoma
Visual Identification: Clear colorless to pale yellow liquid, practically free from visible particles.; Container Type: Bottle; Container Material: LDPE; Container Life Time: 3 Years; Container Temperature: Store below 30 degrees Celsius
Registered
2018-07-03
TIMOEYE 0.25% AND 0.5% EYE DROPS SOLUTION _TIMOLOL MALEATE_ CONSUMER MEDICINE INFORMATION (CMI) SUMMARY The full CMI on the next page has more details. If you are worried about using this medicine, speak to your doctor or pharmacist. 1. WHY AM I USING TIMOEYE? TIMOEYE 0.25% contains 3.4 mg of timolol maleate as Timolol. TIMOEYE 0.5% contains 6.8 mg of timolol maleate as Timolol. TIMOEYE is used to lower raised pressure in the eye and to treat glaucoma. For more information, see Section 1. Why am I using TIMOEYE? in the full CMI. 2. WHAT SHOULD I KNOW BEFORE I USE TIMOEYE? Do not use if you have ever had an allergic reaction to TIMOEYE or any of the ingredients listed at the end of the CMI. TALK TO YOUR DOCTOR IF YOU HAVE ANY OTHER MEDICAL CONDITIONS, TAKE ANY OTHER MEDICINES, OR ARE PREGNANT OR PLAN TO BECOME PREGNANT OR ARE BREASTFEEDING. For more information, see Section 2. What should I know before I use TIMOEYE? in the full CMI. 3. WHAT IF I AM TAKING OTHER MEDICINES? Some medicines may interfere with TIMOEYE and affect how it works. A list of these medicines is in Section 3.What if I am taking other medicines? in the full CMI. 4. HOW DO I USE TIMOEYE? Your doctor will tell you how many drops to take each day. The usual dose for adults is one drop of TIMOEYE twice a day, in either one or both eyes. More instructions can be found in Section 4. How do I use TIMOEYE? in the full CMI. 5. WHAT SHOULD I KNOW WHILE USING TIMOEYE? THINGS YOU SHOULD DO Remind any doctor, dentist or pharmacist you visit that you are using TIMOEYE THINGS YOU SHOULD NOT DO Do not give TIMOEYE to anyone else, even if they have the same condition as you. Do not stop using TIMOEYE without first talking to your doctor. DRIVING OR USING MACHINES Be careful driving or operating machinery until you know how TIMOEYE affects you. LOOKING AFTER YOUR MEDICINE Keep your eye drops in a cool place where the temperature stays below 30ºC. Do not store it or any other medicine in the bathroom or near a sink. For more information see Section 5. W সম্পূর্ণ নথি পড়ুন
PRODUCT INFORMATION TIMOEYE 0.25% AND 0.5% EYE DROPS SOLUTION NAME OF THE MEDICINE AUSTRALIAN APPROVED NAME Timolol maleate CAS NUMBER: 26921-17-5 CHEMICAL STRUCTURE Timolol maleate is described chemically as (S)-1-((1,1-dimethylethyl)amino)-3-((4-(4- morpholinyl) -1,2,5-thiadiazol-3-yl)oxy)-2-propanol, (Z)-butenedioate(1:1)salt. Timolol maleate possesses an asymmetric carbon atom in its structure and is provided as the levo isomer. The empirical formula is C 13 H 24 N 4 O 3 S.C 4 H 4 O 4 and the structural formula is: DESCRIPTION Timolol maleate has a molecular weight of 432.50. It is a white or almost white, crystalline powder or colourless crystals which is soluble in water, and ethanol(96%). TIMOEYE is stable at room temperature TIMOEYE eye drops is clear colorless to pale yellow liquid, practically free from visible particles. The inactive ingredients are: benzalkonium chloride as preservative agent, monobasic sodium phosphate dihydrate, dibasic sodium phosphate dodecahydrate, sodium hydroxide for pH adjustment, water for injections. PHARMACOLOGY Timolol maleate is a non-selective beta-adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anaesthetic (membrane-stabilising) activity. Timolol maleate combines reversibly with a part of the cell membrane, the beta-adrenergic receptor, and thus inhibits the usual biological response that would occur with stimulation of that receptor. This specific competitive antagonism blocks stimulation of the beta-adrenergic receptors by catecholamines having beta-adrenergic stimulating (agonist) activity, whether these originate from an endogenous or exogenous source. Reversal of this blockade can be accomplished by increasing the concentration of the agonist, which will restore the usual biological response. Ophthalmic Solution timolol (timolol maleate) reduces elevated and normal intraocular pressure whether or not associated with glaucoma. Elevated intraocular pressure is a major risk factor in t সম্পূর্ণ নথি পড়ুন