Country: মাল্যাশিয়া
ভাষা: ইংরেজি
সূত্র: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
TADALAFIL
RANBAXY (MALAYSIA) SDN. BHD.
TADALAFIL
4 Tablets
Sun Pharmaceutical Industries Limited
TALIS 20 (TADALAFIL TABLETS 20MG) Page 1 TALIS 20 (Tadalafil Tablets 20mg)_ _ _Consumer Medication Information Leaflet (RiMUP) _ WHAT IS IN THIS LEAFLET 1. What TALIS 20 are used for 2. How TALIS 20 work 3. Before you use TALIS 20 4. How to use TALIS 20 5. While you are using it 6. Side effects 7. Storage and Disposal of TALIS 20 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT TALIS 20 ARE USED FOR TALIS 20 contain the active ingredient tadalafil. Tadalafil is used to treat adult men with: erectile dysfunction, also known as impotence, in men. This is when a man cannot get, or maintain, a hard erect penis suitable for sexual activity. HOW TALIS 20 WORK ERECTILE DYSFUNCTION Following sexual stimulation tadalafil works by helping the blood vessels in your penis to relax, allowing the flow of blood into your penis. The result of this is improved erectile function. Tadalafil will not help you if you do not have erectile dysfunction. It is important to note that tadalafil for the treatment of erectile dysfunction does not work if there is no sexual stimulation. You and your partner will need to engage in foreplay, just as you would if you were not taking a medicine for erectile dysfunction. BEFORE YOU USE TALIS 20 _ _ _WHEN YOU MUST NOT USE IT _ DO NOT TAKE TALIS 20: if you are allergic to tadalafil or any of the other ingredients of this medicine (see product description at the end of this leaflet). An allergic reaction may include skin rash, itching, swelling of the face, lips, tongue and throat or difficulty in breathing. if you are currently taking any nitrates or amyl nitrite (medicines used to treat chest pain). if you have serious heart disease or recently had a heart attack within the last 90 days. if you recently had a stroke within the last 6 months if you have low blood pressure or unco সম্পূর্ণ নথি পড়ুন
_For the use of a Registered Medical Practitioner only _ PRESCRIBING INFORMATION TALIS 20 (TADALAFIL TABLETS USP 20 MG) COMPOSITION Each TALIS 20 mg tablet contains 20 mg Tadalafil. _List of excipients _ Poloxamer (188) (Lutrol F 68), Hydroxy Propyl cellulose, Lactose Monohydrate, Crosspovidone, Microcrystalline cellulose, Crosspovidone, Microcrystalline cellulose, Colloidal Anhydrous Silica, Magnesium Stearate DESCRIPTION 1 TALIS 20 is a Yellow colored, oval shaped, biconvex, film coated tablets plain on both the sides. TALIS 20 contains tadalafil which is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES 1 PHARMACODYNAMICS _MECHANISM OF ACTION _ Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP) ‐ specific phosphodiesterase type 5 (PDE5). When sexual stimulation causes the local release of nitric oxide, inhibition of PDE5 by tadalafil produces increased levels of cGMP in the corpus cavernosum. This results in smooth muscle relaxation and inflow of blood into the penile tissues, thereby producing an erection. Tadalafil has no effect in the treatment of erectile dysfunction (ED) in the absence of sexual stimulation. _PHARMACODYNAMIC EFFECTS _ Tadalafil is a selective inhibitor of PDE5. PDE5 is an enzyme found in the smooth muscle of the corpus cavernosum, prostate and bladder as well as in vascular and visceral smooth muscle, skeletal muscle, platelets, kidney, lung, cerebellum and pancreas. The effect of tadalafil is more potent on PDE5 than on other phosphodiesterases. PHARMACOKINETICS Tadalafil is readily absorbed after oral administration and the mean maximum observed plasma concentration (Cmax) is reported to be achieved at a median time of 2 hours after dosing. Absolute bioavailability of tadalafil following oral dosing has not been determined. The rate and extent of absorption of tadalafil are not influenced by food, thus tadalafil may be taken with or wit সম্পূর্ণ নথি পড়ুন