SODIUM BICARBONATE INJECTION, USP Solution

Country: কানাডা

ভাষা: ফরাসি

সূত্র: Health Canada

সক্রিয় উপাদান:

Bicarbonate de sodium

থেকে পাওয়া:

FRESENIUS KABI CANADA LTD

এটিসি কোড:

B05XA02

INN (International Name):

SODIUM BICARBONATE

ডোজ:

84MG

ফার্মাসিউটিকাল ফর্ম:

Solution

রচনা:

Bicarbonate de sodium 84MG

প্রশাসন রুট:

Intraveineuse

প্যাকেজ ইউনিট:

15G/50G

প্রেসক্রিপশন টাইপ:

Spécialité médicale

Therapeutic area:

ALKALINIZING AGENTS

পণ্য সারাংশ:

Numéro de groupe d'ingrédients actifs (GIA) :0104153005; AHFS:

অনুমোদন অবস্থা:

APPROUVÉ

অনুমোদন তারিখ:

2019-03-12

পণ্য বৈশিষ্ট্য

2
PRESCRIBING INFORMATION
SODIUM BICARBONATE INJECTION, USP
42 MG / ML (4.2%), 84 MG / ML (8.4%)
STERILE SOLUTION
ALKALIZER
_FOR CORRECTION OF METABOLIC ACIDOSIS AND OTHER CONDITIONS REQUIRING
SYSTEMIC _
_ALKALINIZATION_
Fresenius Kabi Canada Ltd.
165 Galaxy Blvd, Suite 100
Toronto, ON M9W 0C8
Date of Preparation:
March 12, 2019
Submission Control Number: 216164
Sodium Bicarbonate Injection, USP
Page 2 of 6
PRESCRIBING INFORMATION
SODIUM BICARBONATE INJECTION, USP
42 MG / ML (4.2%), 84 MG / ML (8.4%)
STERILE SOLUTION
ALKALIZER
_FOR CORRECTION OF METABOLIC ACIDOSIS AND OTHER CONDITIONS REQUIRING _
_SYSTEMIC ALKALINIZATION_
ACTION AND CLINICAL PHARMACOLOGY
Intravenous sodium bicarbonate therapy increases plasma bicarbonate,
buffers excess hydrogen ion
concentration, raises blood pH and reverses the clinical
manifestations of acidosis.
Sodium bicarbonate in water dissociates to provide sodium (Na
+
) and bicarbonate (HCO
3
-
) ions. Sodium (Na
+
)
is the principal cation of extracellular fluid and plays a large part
in the therapy of fluid and electrolyte
disturbances. Bicarbonate (HCO
3
-
) is a normal constituent of body fluids and the normal plasma level
ranges
from 24 to 31 mmol (mEq) / liter. Plasma concentration is regulated by
the kidney through acidification of the
urine when there is a deficit or by alkalinization of the urine when
there is an excess. Bicarbonate anion is
considered “labile” since at a proper concentration of hydrogen
ion (H
+
) it may be converted to carbonic acid
(H
2
CO
3
) and thence to its volatile form, carbon dioxide (CO
2
) excreted by the lung. Normally a ratio of 1:20
(carbonic acid: bicarbonate) is present in the extracellular fluid. In
a healthy adult with normal kidney
function, practically all the glomerular filtered bicarbonate ion is
reabsorbed; less than 1% is excreted in the
urine.
INDICATIONS AND CLINICAL USE
Sodium Bicarbonate Injection, USP is indicated in the treatment of
metabolic acidosis which may occur in
severe renal disease, uncontrolled diabetes, circulatory