PROPRANOLOL HYDROCHLORIDE tablet PROPRANOLOL HYDROCHLORIDE tablet

দেশ: মার্কিন যুক্তরাষ্ট্র

ভাষা: ইংরেজি

সূত্র: NLM (National Library of Medicine)

সক্রিয় উপাদান:

PROPRANOLOL HYDROCHLORIDE (UNII: F8A3652H1V) (PROPRANOLOL - UNII:9Y8NXQ24VQ)

থেকে পাওয়া:

AMICI PHARMACEUTICALS LLC

প্রশাসন রুট:

ORAL

প্রেসক্রিপশন টাইপ:

PRESCRIPTION DRUG

থেরাপিউটিক ইঙ্গিত:

Propranolol hydrochloride tablets, USP are indicated in the management of hypertension. They may be used alone or used in combination with other antihypertensive agents, particularly a thiazide diuretic. Propranolol hydrochloride tablets, USP are not indicated in the management of hypertensive emergencies. Propranolol hydrochloride tablets, USP are indicated to decrease angina frequency and increase exercise tolerance in patients with angina pectoris. Propranolol hydrochloride tablets, USP are indicated to control ventricular rate in patients with atrial fibrillation and a rapid ventricular response. Propranolol hydrochloride tablets, USP are indicated to reduce cardiovascular mortality in patients who have survived the acute phase of myocardial infarction and are clinically stable. Propranolol hydrochloride tablets, USP are indicated for the prophylaxis of common migraine headache. The efficacy of propranolol in the treatment of a migraine attack that has started has not been established, and propranolol is

পণ্য সারাংশ:

Propranolol Hydrochloride Tablets, USP 10 mg – Orange, round biconvex scored tablets with “I” “156” on one side and other side plain. They are available as follows: Bottles of 100 Tablets   NDC 69292-530-01 Bottles of 1000 Tablets NDC 69292-530-10 20 mg – Blue, round biconvex scored tablets with “I” “157” on one side and other side plain. They are available as follows: Bottles of 100 Tablets   NDC 69292-532-01 Bottles of 1000 Tablets NDC 69292-532-10 40 mg – Green, round biconvex scored tablets with “I” “159” on one side and other side plain. They are available as follows: Bottles of 100 Tablets   NDC 69292-534-01 Bottles of 1000 Tablets NDC 69292-534-10 60 mg – Pink, round biconvex scored tablets with “I” “160” on one side and other side plain. They are available as follows: Bottles of 100 Tablets   NDC 69292-536-01 Bottles of 1000 Tablets NDC 69292-536-10 80 mg – Yellow, round biconvex scored tablets with “I” “161” on one side and other side plain. They are available as follows: Bottles of 100 Tablets   NDC 69292-538-01 Bottles of 500 Tablets   NDC 69292-538-50 Bottles of 1000 Tablets NDC 69292-538-10

অনুমোদন অবস্থা:

Abbreviated New Drug Application

পণ্য বৈশিষ্ট্য

PROPRANOLOL HYDROCHLORIDE- PROPRANOLOL HYDROCHLORIDE TABLET
PROPRANOLOL HYDROCHLORIDE- PROPRANOLOL HYDROCHLORIDE TABLET
AMICI PHARMACEUTICALS LLC
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PROPRANOLOL HYDROCHLORIDE TABLETS, USPRX
DESCRIPTION
Propranolol hydrochloride, USP is a synthetic beta-adrenergic receptor
blocking agent
chemically described as 2-Propanol,
1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-,
hydrochloride,(±)-.
Its structural formula is:
C
​H
​NO ​HCl M.W. 295.80
Propranolol hydrochloride, USP is a stable, white, crystalline solid
which is readily soluble
in water and in ethanol.
Propranolol hydrochloride tablets, USP are available as tablets for
oral administration
containing either 10 mg, 20 mg, 40 mg, 60 mg, or 80 mg of propranolol
hydrochloride,
USP.
Propranolol hydrochloride tablets, USP also contain colloidal silicon
dioxide,
croscarmellose sodium, lactose monohydrate, magnesium stearate,
microcrystalline
cellulose. Color additives include FD&C Yellow no. 6 aluminum lake (10
mg and 80 mg),
D&C Yellow no. 10 aluminum lake (40 mg and 80 mg), FD&C Blue no. 1
aluminum lake
(20 mg and 40 mg) and FD&C Red no. 40 aluminum lake (60 mg).
CLINICAL PHARMACOLOGY
GENERAL
Propranolol is a nonselective beta-adrenergic receptor blocking agent
possessing no
other autonomic nervous system activity. It specifically competes with
beta-adrenergic
receptor agonist agents for available receptor sites. When access to
beta-receptor sites
is blocked by propranolol, the chronotropic, inotropic, and
vasodilator responses to
beta-adrenergic stimulation are decreased proportionately. At dosages
greater than
required for beta-blockade, propranolol also exerts a quinidine-like
or anesthetic-like
membrane action, which affects the cardiac action potential. The
significance of the
membrane action in the treatment of arrhythmias is uncertain.
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​21
​2
membrane action in the treatment of arrhythmias is uncertain.
MECHANISM OF ACTION
The mechanism of the antihypertensive effect of propranolol has not
been established.
Factors that may contrib