OESTRODOSE 0.06% GEL

Country: মাল্যাশিয়া

ভাষা: ইংরেজি

সূত্র: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

সক্রিয় উপাদান:

ESTRADIOL HEMIHYDRATE (ESTRADIOL)

থেকে পাওয়া:

SYARIKAT WELLCHEM SDN. BHD.

INN (International Name):

ESTRADIOL HEMIHYDRATE (ESTRADIOL)

প্যাকেজ ইউনিট:

80gm mcg/mL

Manufactured by:

Delpharm Drogenbos S.A

তথ্য লিফলেট

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
OESTRODOSE GEL

Estradiol Hemihydrate (60mg/100g)

WHAT IS IN THIS LEAFLET
1.
What Oestrodose is used for
2.
How Oestrodose works
3.
Before you use
Oestrodose
4.
How to use Oestrodose
5.
While you are using it
6.
Side effects
7.
Storage and Disposal
of Oestrodose
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of Revision
WHAT OESTRODOSE IS USED FOR
Oestrodose is used for general
estrogen therapy that is absorbed
through the skin. It contains the
female hormone oestrogen.
Oestrodose is indicated for
estrogen deficiency, following the
decrease in ovarian activity:
-
Blood vessels constriction
dilation disorders, hot flushes.
- Vaginal dryness and thinning
of vaginal wall which may
disrupt sexual intercourse.
HOW OESTRODOSE WORKS
Oestrodose works by replacing the
oestrogen in your body.
BEFORE YOU USE OESTRODOSE
-
_When you must not use it _
Do not take Oestrodose:
-
If you are allergic to estradiol or
any of the other ingredients of
this medicine.
-
If you are pregnant.
-
If you have malignant tumors of
the breast or uterus, pituitary
tumors.
-
If you have severe liver, kidney
or heart disease, porphyria (a
group of diseases in which
substances called porphyrins
build up, affecting the skin or
nervous system)
, blood
circulation disorders such as
blood clots in the veins of the
legs or the lungs or a confirmed
history of these conditions.
-
If you have undiagnosed
vaginal bleeding.
A complete medical and family
history should be obtained prior to
starting any estrogen therapy.
Before commencing therapy, you
should have a complete physical and
gynaecological examination including
blood pressure, breasts, abdomen and
pelvic organs and endometrial
assessment where necessary. This
should be repeated at regular intervals.
People with a uterus should be
monitored at least annually for signs
of thickening of uterus lining or
endometrial cancer.
Women who have not had their uterus
removed. The addition of 10 or more
days of progest

পণ্য বৈশিষ্ট্য

oEsrRooosE
0.06%
metered
dose
pump.
tttod. of
actiot
:
General
6trc9cr
therapy
v€
the
perclulncoqs
rEdc:
Uses
the
natural cslrogen s€crcted by the o!'ary
: 170
-
estr-r'dd
!
Ph.tmacology:
.
Generat
6uoger! lherapy by
the
percutaneous
rouic, wrtlt
Urr
iolloring
ad\€ntag6:
Use
cl frcl
estrogen
natuially secreled by the
qvary
.
namely
6tradid
l7!l
.
Avords the 6,ft€cts
of
fi6t
pas3age
through
the
lrver.
wii$
incrlas€s
aogitlosirDgrn
sFlth6is.
VLOL lipopotans
and
c?rtarn doning
factoi.s
@nlrdcfed
to fa\rour
the
da,eb',mdrt
d
carOio
vascular. thrombocmbotic
and mclabolic sidedtects.
P
h
a rm a c ok i t,edc
p,oo{,n
i es :
Percutan€ous
absorp0on
equal
to a.ound
10%
of the
(bs€
apptied:me
mctcfed
dos€
delweed
75pg c{ estradid.
There ts transrtory
slockage in
th.
fr.nc€l
oa tha "pidermis_Thara
is
stow
ditfusroo
into
the
general
crrcubtron
via
the
d€rmic capitbry
b€d. The
pbsrna
br€l
c,
t7g
I
estradbl
obtaiDed
in menopausal rc.nen
r€ceiving
2 m€assures
perdayof
Ocnaodb6€
b
m
average
80
pg
, ml. Th€ sslrone / estradioi rato
as
sin
ar to
that seen in
nonfiau€usal
genifally
aclive
trornen.
Activa ingndieat
Tl$s
can€tcr dcli/ers
6il
m€tercd dot€5
Each
m€te.ld
dos!
(
1,25
g
9€l
)
cq|tarns 0.75 mg
t7p-€3rradEi
Oth.r
ingr.diqr6:
fu{trc!.
95%
v/v
clhard.
tnelhar|ob|'iru
a.}d
lndicatioas .
lodicated
in
Etrogen
deficrency
tollowrng
lhe decre.ase
in
o.arian
activitl
-
vasomolors disotdeG.
ho{ nushes
-
vaginal
alrophy
and dryn6s
wh|ch
may
disrupt
sexual
ir ercou6e.
contlaindiczuons:
Malignarf tumors
of tie
breasl
q
uterus.
pituiEry
tumors
sever€
hepatrc.
aenal
or
cardiac
drs€ase.
porphyria.
actrye
deep vem
thrsnbosis.
disordeG
or a confirmed
history
of tlrse condilions.
Undiagnosed
vagtnal
bleeding.
o
(r
Wqnco
who
ha'rr
id
had
fhat
uteru3
r"movd'
Tht a"dtton
d
lO
s
mat
dtF
d
Pt€ef,ffitr'
;il;'il
il
;0,
-tqn
(by
c,
ch.!o.b.
rhr*y
|3 b
pn*d
.e.ni
h'p..Phs
cfstg..
d
|'ra
aa
bftatnum
irsa th|3
ttt
dst
C
RERTLLY
h tlt
lo'loimg
caG:
il#;.
;d
p*,
ffi,
lcrdy
c, b.arr
dEr,
livtr
tunctir
d!dd.