NUELIN-SR 250 TABLET

দেশ: সিঙ্গাপুর

ভাষা: ইংরেজি

সূত্র: HSA (Health Sciences Authority)

সক্রিয় উপাদান:

THEOPHYLLINE ANHYDROUS

থেকে পাওয়া:

INOVA PHARMACEUTICALS (SINGAPORE) PTE. LIMITED

এটিসি কোড:

R03DA04

ডোজ:

250 mg

ফার্মাসিউটিকাল ফর্ম:

TABLET

রচনা:

THEOPHYLLINE ANHYDROUS 250 mg

প্রশাসন রুট:

ORAL

প্রেসক্রিপশন টাইপ:

Prescription Only

Manufactured by:

Adcock Ingram Limited

অনুমোদন অবস্থা:

ACTIVE

অনুমোদন তারিখ:

1999-01-20

তথ্য লিফলেট

PLEASE NOTE: THIS IS A LOW RESOLUTION PDF & IS NOT TO BE USED AS
FINAL ARTWORK
Comments
VERSION 
1
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95
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Signatures
25.04.14 - New artwork build - Schee
12.08.14 - Add Revision Date - Schee
DATE ....................................
25.04.14
LEAD MARKETING COUNTRY..............
Australia
ARTWORK SOFTWARE ................
Illustrator CS6
BRAND .......................................
Nuelin
PRODUCT VARIANT .....................................
................................................Nuelin 500 Tabs
CONSUMER UNIT CONTENT ..........
125&250mg
COMPONENT ..................................
Leaflet
PROJECT..........................................
XXXXX
FILE NAME.
69197_LT007401<008401_Nuelin_500Tabs_125&250mg_Leaflet.ai
IMPORTANT: PDF’s are for viewing only.
They are NOT to be used for Final Artwork.
Colour
100%
BLACK
LT007401/LT008401
69197
COMPOSITION:  Nuelin SR contains 125mg, 200mg, 250mg or 300mg
anhydrous theophylline (1,3-dimethyl xanthine, also named
3,7-dihydro  
1,3-dimethyl- purine-2,6(1H)-dione) in the form of sustained release
tablets. Nuelin SR contains the following excipients: guar gum,
magnesium stearate 
and purified water.
PHARMACOLOGY
SITE AND MODE OF ACTION: Theophylline has a direct relaxant effect on
the smooth muscle of bronchial airways and pulmonary blood vessels,
serving as 
a bronchodilator and pulmonary vasodilator. It also exhibits
activities typical of xanthines such as CNS stimulation including the
respiratory centre, 
cardiac stimulation, coronary vasodilatation, diuresis and increased
gastric secretion. The mechanism of action of theophylline in vivo
has not been fully 
elucidated. One mechanism of smooth muscle relaxation may be
inhibition of phosphodiesterase that reduces intracellular hydrolysis
of cyclic AMP. 
Increased intracellular concentrations of cyclic AMP have been
associated with relaxation of bronchial smooth muscle. There is no
evidence that 
tolerance develops with continued use of theophyll

পণ্য বৈশিষ্ট্য

PRODUCT
BRAND: Nuelin
PRODUCT VARIANT:
PACK SIZE: 500 Tablets
COUNTRY: SG, HK, LK
DATE: 12/07/2018
COMPONENT: Leaflet
DIMENSIONS: 140mm w x 200mm h
FILENAME:
81880_LT0028_Nuelin_Bronchodilator_
500_Leaflet_SG_HK_LK_V1.ai
DIELINE REF: XXX
BLACK
PRINTER: XXX
ARTWORK SOFTWARE: Illustrator CC 2017
BARCODE %:
SIGNED:
ARTWORKER:
DATE: 00/00/2018
EMO: Adcock
SKU NO: 100074, 100084
PRINTER DETAILS
FONTS USED:
BODY COPY SIZE: 6pts
MIN. FONT SIZE: 1.24mm
FONTS
CODES
APPROVALS
UIC: LT0028
27/04/18 : New Artwork Build - Elaine
12/07/18 : Text Amends - Sunny
AMENDS
ARTWORKER INFO
COLOURS
VERSION: 1
JOB NO: 81880
PLEASE NOTE: THIS IS A LOW RESOLUTION PDF & IS NOT TO BE USED FOR
PRINTING
Helvetica Bold
Helvetica Bold
Helvetica Condensed Medium
Helvetica Condensed Bold
Swiss 721 BT
Myriad Pro
Helvetica.Condensed Oblique
Bronchodilator
COMPOSITION: Nuelin SR contains 125mg, 200mg, 250mg or 300mg anhydrous
theophylline (1,3-dimethyl xanthine, also named 3,7-dihydro
1,3-dimethyl- purine-2,6(1H)-dione) in the form of sustained release
tablets. Nuelin SR contains the following excipients: guar gum,
magnesium stearate
and purified water.
PHARMACOLOGY
SITE AND MODE OF ACTION: Theophylline has a direct relaxant effect on
the smooth muscle of bronchial airways and pulmonary blood vessels,
serving as
a bronchodilator and pulmonary vasodilator. It also exhibits
activities typical of xanthines such as CNS stimulation including the
respiratory centre,
cardiac stimulation, coronary vasodilatation, diuresis and increased
gastric secretion. The mechanism of action of theophylline in vivo has
not been fully
elucidated. One mechanism of smooth muscle relaxation may be
inhibition of phosphodiesterase that reduces intracellular hydrolysis
of cyclic AMP.
Increased intracellular concentrations of cyclic AMP have been
associated with relaxation of bronchial smooth muscle. There is no
evidence that
tolerance develops with continued use of theophylline.
RELATIONSHIP TO OTHER DRUGS: Theophylline is closely related to the
other xanthines, caffeine and the