MIOCHOL-E INTRAOCULAR SOLUTION

দেশ: সিঙ্গাপুর

ভাষা: ইংরেজি

সূত্র: HSA (Health Sciences Authority)

সক্রিয় উপাদান:

ACETYLCHOLINE CHLORIDE

থেকে পাওয়া:

BAUSCH & LOMB (SINGAPORE) PRIVATE LIMITED

এটিসি কোড:

S01EB09

ডোজ:

20 mg/2 ml

ফার্মাসিউটিকাল ফর্ম:

INJECTION

রচনা:

ACETYLCHOLINE CHLORIDE 20 mg/2 ml

প্রশাসন রুট:

INTRAOCULAR

প্রেসক্রিপশন টাইপ:

General Sale List

Manufactured by:

Novartis Pharma Stein AG

অনুমোদন অবস্থা:

ACTIVE

অনুমোদন তারিখ:

1997-03-18

তথ্য লিফলেট

Miochol
®
-E
Parasympathomimetic
COMPOSITION AND 
PHARMACEUTICAL FORM 
Each vial contains 20 mg acetylcholine chloride. 
Miochol
®
-E contains 10mg/ml of acetylcholine 
chloride (20 mg in 2 ml) upon reconstitution. 
For excipients, see section 
EXCIPIENTS.
Powder and solvent for instillation solution 
for intraocular use. Miochol
®
-E is presented 
in a blister pack containing one vial and 
one ampoule; the vial contains 20 mg of 
acetylcholine chlor ide; the ampoule contains 
2 ml of solvent. The reconstituted preparation is 
a clear, colourless solution. 

INDICATIONS 
Miochol
®
-E is used to obtain miosis of the iris 
in seconds after placement of the intraocular 
lens (IOL) in cataract surgery and in penetrating 
keratoplasty, iridectomy and other anterior 
segment surgery where rapid miosis may 
be required. 
DOSAGE AND ADMINISTRATION
ADULTS AND ELDERLY 
In most cases, 0.5 to 2 ml produces 
satisfactory miosis. 
The syringe containing the reconstituted 
preparation must be fitted with a suitable 
irrigation cannula for intraocular irrigation. The 
Miochol
®
-E solution is instilled into the anterior 
chamber before or after securing one or more 
sutures. Instillation should be gentle and parallel 
to the iris face and tangential to the pupil border.

If there are no mechanical hindrances, the pupil 
starts to constrict in seconds and the peripheral 
iris is drawn away from the angle of the anterior 
chamber. Any anatomical hindrance to miosis, 
such as anterior or posterior synechiae, must be 
released to permit the desired effect of the drug. 
The solution should be reconstituted 
immediately before use since aqueous solutions 
of acetylcholine are unstable. 
PAEDIATRIC USE 
Safety and effectiveness in children have not 
been established. 
CONTRAINDICATIONS 
Hypersensitivity to the active substance or to 
any of the excipients.
SPECIAL WARNINGS AND 
PRECAUTIONS FOR USE 
In cataract surgery, use Miochol
®
-E only after 
placement of the IOL. 
INTE

পণ্য বৈশিষ্ট্য

Miochol
®
-E
Parasympathomimetic
COMPOSITION AND
PHARMACEUTICAL FORM
Each vial contains 20 mg acetylcholine chloride.
Miochol
®
-E contains 10mg/ml of acetylcholine
chloride (20 mg in 2 ml) upon reconstitution.
For excipients, see section EXCIPIENTS.
Powder and solvent for instillation solution
for intraocular use. Miochol
®
-E is presented
in a blister pack containing one vial and
one ampoule; the vial contains 20 mg of
acetylcholine chlor ide; the ampoule contains
2 ml of solvent. The reconstituted preparation is
a clear, colourless solution.
INDICATIONS
Miochol
®
-E is used to obtain miosis of the iris
in seconds after placement of the intraocular
lens (IOL) in cataract surgery and in penetrating
keratoplasty, iridectomy and other anterior
segment surgery where rapid miosis may
be required.
DOSAGE AND ADMINISTRATION
ADULTS AND ELDERLY
In most cases, 0.5 to 2 ml produces
satisfactory miosis.
The syringe containing the reconstituted
preparation must be fitted with a suitable
irrigation cannula for intraocular irrigation. The
Miochol
®
-E solution is instilled into the anterior
chamber before or after securing one or more
sutures. Instillation should be gentle and parallel
to the iris face and tangential to the pupil border.
If there are no mechanical hindrances, the pupil
starts to constrict in seconds and the peripheral
iris is drawn away from the angle of the anterior
chamber. Any anatomical hindrance to miosis,
such as anterior or posterior synechiae, must be
released to permit the desired effect of the drug.
The solution should be reconstituted
immediately before use since aqueous solutions
of acetylcholine are unstable.
PAEDIATRIC USE
Safety and effectiveness in children have not
been established.
CONTRAINDICATIONS
Hypersensitivity to the active substance or to
any of the excipients.
SPECIAL WARNINGS AND
PRECAUTIONS FOR USE
In cataract surgery, use Miochol
®
-E only after
placement of the IOL.
INTERACTIONS
None known
PREGNANCY AND LACTATION
PREGNANCY
Animal reproduction studies have not been
conducte