MELOXICAM tablet

দেশ: মার্কিন যুক্তরাষ্ট্র

ভাষা: ইংরেজি

সূত্র: NLM (National Library of Medicine)

এখন এটা কিনুন

সক্রিয় উপাদান:

MELOXICAM (UNII: VG2QF83CGL) (MELOXICAM - UNII:VG2QF83CGL)

থেকে পাওয়া:

Quality Care Products LLC

প্রশাসন রুট:

ORAL

প্রেসক্রিপশন টাইপ:

PRESCRIPTION DRUG

থেরাপিউটিক ইঙ্গিত:

INDICATIONS AND USAGE Carefully consider the potential benefits and risks of meloxicam and other treatment options before deciding to use meloxicam. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS ). Meloxicam is indicated for relief of the signs and symptoms of osteoarthritis and rheumatoid arthritis. CONTRAINDICATIONS Meloxicam is contraindicated in patients with known hypersensitivity to meloxicam. Meloxicam should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactic-like reactions to NSAIDs have been reported in such patients (see WARNINGS , Anaphylactoid Reactions , and PRECAUTIONS , Pre-existing Asthma ). Meloxicam is contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery (see WARNINGS ).

পণ্য সারাংশ:

HOW SUPPLIED Meloxicam Tablets USP are available as light yellow, round, flat, uncoated tablets containing meloxicam 7.5 mg or as light yellow, oblong, biconvex, uncoated tablets containing meloxicam 15 mg. The 7.5 mg tablet is impressed with letter U and L on one side and tablet code 7.5 on the other side. The 15 mg tablet is impressed with letter U and L on one side and tablet code 15 on the other side. Meloxicam Tablets USP 7.5 mg are available as follows: Meloxicam Tablets USP 15 mg are available as follows: 49999-869-15 49999-869-30 49999-869-60 49999-869-90

অনুমোদন অবস্থা:

Abbreviated New Drug Application

তথ্য লিফলেট

                                MELOXICAM- MELOXICAM TABLET
Quality Care Products LLC
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MELOXICAM - meloxicam tablet
Unichem Pharmaceuticals (USA), Inc.
----------
Meloxicam Tablets USP 7.5 mg and 15 mg
Meloxicam Tablets USP 7.5 mg and 15 mg
Medication Guide for Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
(See the end of this Medication Guide for a list of prescription NSAID
medicines).
What is the most important information I should know about medicines
called Non-Steroidal Anti-
Inflammatory Drugs (NSAIDs)?
NSAID medicines may increase the chance of a heart attack or stroke
that can lead to death. This chance
increases:
•
with longer use of NSAID medicines
•
in people who have heart disease
NSAID medicines should never be used right before or after a heart
surgery called a "coronary artery
bypass graft (CABG)."
NSAID medicines can cause ulcers and bleeding in the stomach and
intestines at any time during
treatment. Ulcers and bleeding:
•
can happen without warning symptoms
•
may cause death
The chance of a person getting an ulcer or bleeding increases with:
•
taking medicines called "corticosteroids" and "anticoagulants"
•
longer use
•
smoking
•
drinking alcohol
•
older age
•
having poor health
NSAID medicines should only be used:
•
exactly as prescribed
•
at the lowest dose possible for your treatment
•
for the shortest time needed
What are Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?
NSAID medicines are used to treat pain and redness, swelling, and heat
(inflammation) from medical
conditions such as:
•
different types of arthritis
•
menstrual cramps and other types of short-term pain
Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)?
Do not take an NSAID medicine:
•
if you had an asthma attack, hives, or other allergic reaction with
aspirin or any other NSAID
medicine
•
for pain right before or after heart bypass surgery
Tell your healthcare provider:
•
about all of your medical conditions
•
about all of the medicines you take. NSAIDs and some other medicines
can interact
                                
                                সম্পূর্ণ নথি পড়ুন
                                
                            

পণ্য বৈশিষ্ট্য

                                MELOXICAM- MELOXICAM TABLET
QUALITY CARE PRODUCTS LLC
----------
MELOXICAM 15 MG
DESCRIPTION
Meloxicam, an oxicam derivative, is a member of the enolic acid group
of nonsteroidal
anti-inflammatory drugs (NSAIDs). Each pastel yellow Meloxicam tablet
USP contains 7.5
mg or 15 mg meloxicam for oral administration. Meloxicam is chemically
designated as
4-hydroxy-2-methyl-_N_-(5-methyl-2-thiazolyl)-_2H_-1,2-benzothiazine-3-carboxamide-1,1-
dioxide. The molecular weight is 351.4. Its empirical formula is C
H
N O S and it has
the following structural formula.
Meloxicam is a pastel yellow solid, practically insoluble in water,
with higher solubility
observed in strong acids and bases. It is very slightly soluble in
methanol. Meloxicam has
an apparent partition coefficient (log P)app = 0.1 in
_n_-octanol/buffer pH 7.4. Meloxicam
has pKa values of 1.1 and 4.2.
Meloxicam is available as a tablet for oral administration containing
7.5 mg or 15 mg
meloxicam.
The inactive ingredients in Meloxicam tablets USP include colloidal
silicon dioxide,
crospovidone, lactose monohydrate, magnesium stearate,
microcrystalline cellulose,
povidone and sodium citrate dihydrate.
CLINICAL PHARMACOLOGY
Mechanism of Action
Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that
exhibits anti-
inflammatory, analgesic, and antipyretic activities in animal models.
The mechanism of
action of meloxicam, like that of other NSAIDs, may be related to
prostaglandin
synthetase (cyclo-oxygenase) inhibition.
Pharmacokinetics
_Absorption_
The absolute bioavailability of meloxicam capsules was 89% following a
single oral dose
of 30 mg compared with 30 mg IV bolus injection. Following single
intravenous doses,
dose-proportional pharmacokinetics were shown in the range of 5 mg to
60 mg. After
multiple oral doses the pharmacokinetics of meloxicam capsules were
dose-proportional
over the range of 7.5 mg to 15 mg. Mean C
was achieved within four to five hours
after a 7.5 mg meloxicam tablet was taken under fasted conditions,
indicating prolonged
drug absorp
                                
                                সম্পূর্ণ নথি পড়ুন
                                
                            

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