Country: কানাডা
ভাষা: ইংরেজি
সূত্র: Health Canada
HYDROCORTISONE (HYDROCORTISONE SODIUM SUCCINATE)
TEVA CANADA LIMITED
H02AB09
HYDROCORTISONE
250MG
POWDER FOR SOLUTION
HYDROCORTISONE (HYDROCORTISONE SODIUM SUCCINATE) 250MG
INTRAMUSCULAR
10
Prescription
ADRENALS
Active ingredient group (AIG) number: 0106344004; AHFS:
CANCELLED POST MARKET
2018-04-30
page 1 of 7 PACKAGE INSERT Sterile Powder PR HYDROCORTISONE SODIUM SUCCINATE FOR INJECTION BP _ _ Glucocorticoid _ _ ACTION AND CLINICAL PHARMACOLOGY Hydrocortisone sodium succinate is a corticosteroid, and a highly water soluble ester derivative of hydrocortisone. It has the same metabolic and anti inflammatory actions as hydrocortisone. High blood levels of hydrocortisone are attained following intravenous injection. Pharmacological effects have been noted within minutes and persist for variable periods of time. Excretion occurs primarily within 12 hours so that if high blood levels need to be maintained hydrocortisone injections are to be repeated every 4 to 6 hours. The intravenous route is preferred for initial emergency treatment. INDICATIONS AND CLINICAL USE Corticosteroid therapy is an adjunct to, and not a replacement for, conventional therapy. 1. ENDOCRINE DISORDERS Congenital adrenal hyperplasia; Hypercalcemia associated with cancer; Primary or secondary adrenocortical insufficiency or acute adrenocortical insufficiency (hydrocortisone is the drug of choice - it may also be used to supplement synthetic analogs); Patients with known adrenal insufficiency or when adrenocortical reserve is doubtful; Preoperatively; Serious trauma or illness; Shock unresponsive to conventional therapy if adrenocortical insufficiency exists or is suspected; Nonsuppurative thyroiditis. 2. ALLERGIC STATES Acute non infectious laryngeal oedema (though epinephrine is the drug of first choice); Control of severe or incapacitating allergic reactions: Drug hypersensitivity reactions; Serum sickness; Seasonal or perennial allergic rhinitis; Urticarial transfusion reactions. 3. RESPIRATORY DISEASES Aspiration pneumonitis; Berylliosis; Bronchial asthma; Concurrently with appropriate antituberculous chemotherapy in fulminating or disseminated pulmonary tuberculosis; Loeffler's syndrome not manageable by other means; Symptomatic sarcoidosis. 4. DERMATOLOGIC DISEASES Atopic dermatitis; Bullous dermatitis herpetiformis; Contact dermatiti সম্পূর্ণ নথি পড়ুন