FUROSEMIDE tablet

দেশ: মার্কিন যুক্তরাষ্ট্র

ভাষা: ইংরেজি

সূত্র: NLM (National Library of Medicine)

সক্রিয় উপাদান:

FUROSEMIDE (UNII: 7LXU5N7ZO5) (FUROSEMIDE - UNII:7LXU5N7ZO5)

থেকে পাওয়া:

Aidarex Pharmaceuticals LLC

INN (আন্তর্জাতিক নাম):

FUROSEMIDE

রচনা:

FUROSEMIDE 20 mg

প্রশাসন রুট:

ORAL

প্রেসক্রিপশন টাইপ:

PRESCRIPTION DRUG

থেরাপিউটিক ইঙ্গিত:

FUROSEMIDE TABLET is indicated in adults and pediatric patients for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. FUROSEMIDE TABLET is particularly useful when an agent with greater diuretic potential is desired. Oral FUROSEMIDE TABLET may be used in adults for the treatment of hypertension alone or in combination with other antihypertensive agents. Hypertensive patients who cannot be adequately controlled with thiazides will probably also not be adequately controlled with FUROSEMIDE TABLETS alone. FUROSEMIDE TABLET is contraindicated in patients with anuria and in patients with a history of hypersensitivity to furosemide.

পণ্য সারাংশ:

Furosemide tablets 20 mg are supplied as white to off-white, round, flat face beveled edge, compressed tablets, debossed "EP" and "116" on one side and plain on the other. FUROSEMIDE TABLETS 40 mg are supplied as white, round, scored tablets.  The 40 mg tablets are imprinted with "EP 117" on one side and "40" on the other. Note: Dispense in well-closed, light-resistant containers. Exposure to light might cause a slight discoloration. Discolored tablets should not be dispensed. Store at 25° C (77° F); excursions permitted to 15 to 30° C (59 to 86° F). [See USP Controlled Room Temperature.] Repackaged by Aidarex Pharmaceuticals, LLC Corona, CA 92880

অনুমোদন অবস্থা:

Abbreviated New Drug Application

পণ্য বৈশিষ্ট্য

FUROSEMIDE- FUROSEMIDE TABLET
AIDAREX PHARMACEUTICALS LLC
----------
FUROSEMIDE TABLETS, USP
20 mg, 40 mg, and 80 mg
Rx only
WARNING
FUROSEMIDE TABLET IS A POTENT DIURETIC WHICH, IF GIVEN IN EXCESSIVE
AMOUNTS, CAN LEAD TO A
PROFOUND DIURESIS WITH WATER AND ELECTROLYTE DEPLETION. THEREFORE,
CAREFUL MEDICAL SUPERVISION IS
REQUIRED AND DOSE AND DOSE SCHEDULE MUST BE ADJUSTED TO THE INDIVIDUAL
PATIENT'S NEEDS. (SEE
DOSAGE AND ADMINISTRATION.)
DESCRIPTION
FUROSEMIDE TABLET is a diuretic which is an anthranilic acid
derivative. FUROSEMIDE
TABLET for oral administration contain furosemide as the active
ingredient and the following inactive
ingredients: corn starch, lactose anhydrous, magnesium stearate,
pregelatinized starch, microcrystalline
cellulose, sodium starch Glycolate, and colloidal silicon dioxide.
Chemically, it is 4-chloro-N-
furfuryl- 5-sulfamoylanthranilic acid. FUROSEMIDE TABLET is available
as white tablets for oral
administration in dosage strengths of 20, 40 and 80 mg. Furosemide is
a white to slightly yellow,
odorless crystalline powder. It is practically insoluble in water,
sparingly soluble in alcohol, freely
soluble in dilute alkali solutions and insoluble in dilute acids.
The CAS Registry Number is 54-31-9.
The structural formula is as follows:
CLINICAL PHARMACOLOGY
Investigations into the mode of action of FUROSEMIDE TABLET have
utilized micropuncture studies
in rats, stop flow experiments in dogs and various clearance studies
in both humans and experimental
animals. It has been demonstrated that FUROSEMIDE TABLET inhibits
primarily the absorption of
sodium and chloride not only in the proximal and distal tubules but
also in the loop of Henle. The high
degree of efficacy is largely due to the unique site of action. The
action on the distal tubule is
independent of any inhibitory effect on carbonic anhydrase and
aldosterone.
Recent evidence suggests that furosemide glucuronide is the only or at
least the major
biotransformation product of furosemide in man. Furosemide is
extensively bound to plasm