ENHANCIN SUSPENSION 312.5MG5ML

Country: মাল্যাশিয়া

ভাষা: ইংরেজি

সূত্র: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

সক্রিয় উপাদান:

CLAVULANIC ACID; AMOXYCILLIN

থেকে পাওয়া:

RANBAXY (MALAYSIA) SDN. BHD.

INN (International Name):

CLAVULANIC ACID; AMOXYCILLIN

প্যাকেজ ইউনিট:

60ml mL

Manufactured by:

Sun Pharmaceutical Industries Limited

তথ্য লিফলেট

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
ENHANCIN SUSPENSION
Amoxicillin/clavulanic acid (312.5mg/5mL)
WHAT IS IN THIS LEAFLET
1.
What Enhancin is used for
2.
How Enhancin works
3.
Before you use Enhancin
4.
How to use Enhancin
5.
While you are using Enhancin
6.
Side Effects
7.
Storage and Disposal of Enhancin
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of Revision
11.
Serial Number
WHAT ENHANCIN IS USED FOR
Enhancin is used to treat the following
bacterial infections in different parts of
the body:
•
respiratory tract infections
•
urinary tract infections
•
skin
and
soft
tissue
infections
including dental infections, animal
bites
•
bone and joint infections
HOW ENHANCIN WORKS
Enhancin Suspension is an antibiotic
that
contains
amoxicillin
and
clavulanic acid, which works by killing
bacteria that cause infections.
BEFORE YOU USE ENHANCIN
-
_When you must not use it _
Do not give Enhancin to your child if
they:
•
are
allergic
to
amoxicillin,
clavulanic
acid,
other
penicillin-
based
antibiotics,
or
similar
antibiotics called cephalosporinsor
any of the other ingredients of this
medicine
(listed
in
Product
Description).
•
have ever had liver problems or
jaundice
(yellowing
of
the
skin
and/or whites of the eyes) when
taking an antibiotic.
If you are not sure your child should
take Enhancin Suspension or not, talk
to their doctor or pharmacist before
giving Enhancin.
-
_Before you start to use it _
Tell your doctor if your child:
•
have any viral infections (example,
common cold)
•
are being treated for liver or kidney
problems
•
are not urinating regularly
-
_Taking other medicines _
Tell your doctor if you are taking any
other medicines, including any that you
buy
without
a
prescription
from
a
pharmacy, supermarket or health food
shop.
Tell your doctor or pharmacist if your
child is taking:
•
probenecid,
allopurinol
(medication
to
treat
gout/
joint
disease)
•
warfarin (to prevent blood clot)
•
methotrexate (a medicine used to
treat cancer or rheuma

পণ্য বৈশিষ্ট্য

1
_For the use of a Registered Medical Practitioner Only_
_ _
PRESCRIBING INFORMATION
ENHANCIN SUSPENSION
(AMOXICILLIN AND CLAVULANATE POTASSIUM FOR ORAL SUSPENSION USP)
COMPOSITION
ENHANCIN SUSPENSION
Each 5 ml of the constituted suspension contains:
Amoxicillin USP (as trihydrate)
Equivalent to amoxicillin………………..…………………250
mg
Potassium clavulanate
Equivalent to clavulanic acid ….…………………….……62.5
mg
_EXCIPIENTS:_
Butylated Hydroxytoluene, Xanthan Gum, Monosodium Citrate, Sodium
Citrate, Passion Fruit Flavour,
Aspartame, Sorbitol, Sodium Benzoate
DESCRIPTION
White to off - white powder forming a white to pale yellow suspension
on constitution with water. The resulting
suspension has a characteristic flavour.
PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES
_PHARMACODYNAMIC PROPERTIES_
_ _
Pharmacotherapeutic group: Combinations of penicillins, incl.
Beta-lactamase inhibitors; ATC code:
J01CR02.
Mechanism of action
Amoxicillin is a semisynthetic penicillin (beta-lactam antibiotic)
that inhibits one or more enzymes (often
referred to
as penicillin-binding proteins, PBPs) in the biosynthetic pathway of
bacterial peptidoglycan, which
is an integral
structural component of the bacterial cell wall. Inhibition of
peptidoglycan synthesis leads to
weakening of the
cell wall, which is usually followed by cell lysis and death.
Amoxicillin is susceptible to degradation by beta-lactamases produced
by resistant bacteria and therefore the
spectrum of activity of amoxicillin alone does not include organisms
which produce these enzymes.
Clavulanic acid is a beta-lactam structurally related to penicillins.
It inactivates some b e t a -lactamase
enzymes
thereby preventing inactivation of amoxicillin. Clavulanic acid alone
does not exert a clinically useful
antibacterial
effect.
Pharmacokinetic/pharmacodynamic relationship
The time above the minimum inhibitory concentration (T>MIC) is
considered to be the major determinant of
efficacy for amoxicillin.
2
Mechanisms of resistance
The two m