DOXYCYCLINE HYCLATE tablet

Country: মার্কিন যুক্তরাষ্ট্র

ভাষা: ইংরেজি

সূত্র: NLM (National Library of Medicine)

সক্রিয় উপাদান:

DOXYCYCLINE HYCLATE (UNII: 19XTS3T51U) (DOXYCYCLINE ANHYDROUS - UNII:334895S862)

থেকে পাওয়া:

Actavis Pharma, Inc.

INN (International Name):

DOXYCYCLINE HYCLATE

রচনা:

DOXYCYCLINE ANHYDROUS 50 mg

প্রশাসন রুট:

ORAL

প্রেসক্রিপশন টাইপ:

PRESCRIPTION DRUG

থেরাপিউটিক ইঙ্গিত:

To reduce the development of drug-resistant bacteria and maintain effectiveness of doxycycline hyclate and other antibacterial drugs, doxycycline hyclate should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Doxycycline is indicated for the treatment of the following infections: - Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae. - Respiratory tract infections caused by Mycoplasma pneumoniae . - Lymphogranuloma venereum caused by Chlamydia trachomatis . - Psittacosis (ornithosis) caused by Chlamydophila psittaci . - Trachoma caused by Chlamydia trachomatis , although the infectious agent is not always 

পণ্য সারাংশ:

Doxycycline Hyclate Tablets, USP (equivalent to 100 mg doxycycline) are round, film-coated, light orange, unscored tablets imprinted “DAN ” and “5553 ” supplied in bottles of 50 (NDC 0591-5553-50) and 500 (NDC 0591-5553-05). Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature]. Dispense in a tight, light-resistant container with child-resistant closure.

অনুমোদন অবস্থা:

Abbreviated New Drug Application

পণ্য বৈশিষ্ট্য

DOXYCYCLINE HYCLATE- DOXYCYCLINE HYCLATE TABLET
ACTAVIS PHARMA, INC.
----------
DOXYCYCLINE HYCLATE CAPS AND TABS A062031 A062421
DOXYCYCLINE HYCLATE TABLETS, USP
RX ONLY
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of
doxycycline hyclate and other antibacterial drugs, doxycycline hyclate
should be used
only to treat or prevent infections that are proven or strongly
suspected to be caused
by bacteria.
DESCRIPTION
Doxycycline is an antibacterial drug synthetically derived from
oxytetracycline, and is
available as doxycycline hyclate, USP (doxycycline hydrochloride
hemiethanolate
hemihydrate) for oral administration.
The structural formula of doxycycline hyclate is
with a molecular formula of (C
H
N O •HCl) •C H O•H O and a molecular weight of
1025.89. The chemical designation for doxycycline is
4-(Dimethylamino)-
1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-
naphthacenecarboxamide monohydrochloride, compound with ethyl alcohol
(2:1),
monohydrate. Doxycycline hyclate is a yellow crystalline powder which
is soluble in
water.
Doxycycline has a high degree of lipoid solubility and a low affinity
for calcium binding. It
is highly stable in normal human serum. Doxycycline will not degrade
into an epianhydro
form.
Each tablet, for oral administration, contains doxycycline hyclate,
USP equivalent to 100
mg of doxycycline.
Doxycycline Hyclate Tablets USP, 100 mg contain the following inactive
ingredients:
croscarmellose sodium, FD&C Red No. 40, FD&C Yellow No. 6,
hypromellose,
magnesium stearate, microcrystalline cellulose, polyethylene glycol,
polysorbate 80,
sodium lauryl sulfate and titanium dioxide.
22
24
2
8
2
2
6
2
CLINICAL PHARMACOLOGY
Tetracyclines are readily absorbed and are bound to plasma proteins in
varying degree.
They are concentrated by the liver in the bile and excreted in the
urine and feces at high
concentrations and in a biologically active form. Doxycycline is
virtually completely
absorbed after oral administration.
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