DOXYCYCLINE- doxycycline hyclate tablet, coated

Country: মার্কিন যুক্তরাষ্ট্র

ভাষা: ইংরেজি

সূত্র: NLM (National Library of Medicine)

সক্রিয় উপাদান:

DOXYCYCLINE HYCLATE (UNII: 19XTS3T51U) (DOXYCYCLINE ANHYDROUS - UNII:334895S862)

থেকে পাওয়া:

American Health Packaging

INN (International Name):

DOXYCYCLINE HYCLATE

রচনা:

DOXYCYCLINE ANHYDROUS 100 mg

প্রশাসন রুট:

ORAL

প্রেসক্রিপশন টাইপ:

PRESCRIPTION DRUG

থেরাপিউটিক ইঙ্গিত:

To reduce the development of drug-resistant bacteria and maintain effectiveness of Doxycycline Hyclate Tablets and other antibacterial drugs, Doxycycline Hyclate Tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Doxycycline is indicated for the treatment of the following infections: - Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae . - Respiratory tract infections caused by Mycoplasma pneumoniae . - Lymphogranuloma venereum caused by Chlamydia trachomatis . - Psittacosis (ornithosis) caused by Chlamydophila psittaci . - Trachoma caused by Chlamydia trachomatis , although

পণ্য সারাংশ:

Doxycycline Hyclate Tablets, USP equivalent to 100 mg doxycycline: Orange Coated, Round, Unscored Tablets, Debossed “WW 112”. Unit dose packages of 30 (3 x 10) NDC 62584-693-21 Store at 20° to 25°C (68° to 77°F), [See USP Controlled Room Temperature]. Protect from light and moisture. FOR YOUR PROTECTION: Do not use if blister is torn or broken.

অনুমোদন অবস্থা:

Abbreviated New Drug Application

পণ্য বৈশিষ্ট্য

DOXYCYCLINE- DOXYCYCLINE HYCLATE TABLET, COATED
AMERICAN HEALTH PACKAGING
----------
DOXYCYCLINE HYCLATE TABLETS, USP
8069321/1222
RX ONLY
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of
Doxycycline Hyclate Tablets and other antibacterial drugs, Doxycycline
Hyclate Tablets
should be used only to treat or prevent infections that are proven or
strongly suspected
to be caused by bacteria.
DESCRIPTION
Doxycycline Hyclate Tablets, USP are an antibacterial drug
synthetically derived from
oxytetracycline. The structural formula of doxycycline hyclate is:
with a molecular formula of C
H
N
O
•HCL•1/2C
N
OH•1/2H
O and a molecular
weight of 512.93.
The chemical designation for doxycycline is 2-Naphthacemecarboxamide,
4-
(dimethylamino)-1, 4, 4a, 5, 5a, 6, -11, 12a-octahydro-3,5,10, 12,
12a-pentahydroxy-6-
mothyl-1, 11-dioxo-monohydrochloride, compound with ethanol (2:1),
monohydrate,
[4s-(4α, 4aα, 5α, 5aα, 6α, 12aα)].
Doxycycline is a light-yellow crystalline powder. Doxycycline hyclate
is soluble in water.
Doxycycline has a high degree of lipoid solubility and a low affinity
for calcium binding. It
is highly stable in normal human serum. Doxycycline will not degrade
into an epianhydro
form.
Each tablet for oral administration contains doxycycline hyclate
equivalent to 100 mg of
doxycycline (anhydrous). Inactive ingredients are: Colloidal Silicon
Dioxide, Corn Starch,
Croscarmellose Sodium, Docusate Sodium, Sodium Benzoate, Magnesium
Stearate, and
Microcrystalline Cellulose. Film Coating and Polishing contains: FD&C
Blue No. 2, FD&C
Yellow No. 6, Hydroxypropyl Methylcellulose, Polyethylene Glycol, and
Titanium Dioxide.
22
24
2
8
2
5
2
CLINICAL PHARMACOLOGY
Tetracyclines are readily absorbed and are bound to plasma proteins in
varying degree.
They are concentrated by the liver in the bile and excreted in the
urine and feces at high
concentrations and in a biologically active form. Doxycycline is
virtually completely
absorbed after oral administration.
Following a 200 mg dose