দেশ: যুক্তরাজ্য
ভাষা: ইংরেজি
সূত্র: MHRA (Medicines & Healthcare Products Regulatory Agency)
Desmopressin acetate
Accord-UK Ltd
H01BA02
Desmopressin acetate
10microgram/1dose
Spray
Nasal
No Controlled Drug Status
Valid as a prescribable product
BNF: 06050200; GTIN: 5012617007926
DESMOPRESSIN NASAL SPRAY 10 MICROGRAMS/DOSE READ ALL OF THIS LEAFLET CAREFULLY BEFORE YOU START TAKING THIS MEDICINE. • Keep this leaflet. You may need to read it again. • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. • If you have any further questions, ask your doctor or pharmacist. • If you have any of the side effects, or if you notice any side effects not listed, please tell your doctor or pharmacist. IN THIS LEAFLET: 1 WHAT DESMOPRESSIN IS AND WHAT IT IS USED FOR 2 BEFORE YOU USE DESMOPRESSIN NASAL SPRAY 3 HOW TO USE DESMOPRESSIN NASAL SPRAY 4 POSSIBLE SIDE EFFECTS 5 HOW TO STORE DESMOPRESSIN NASAL SPRAY 6 FURTHER INFORMATION 1 WHAT DESMOPRESSIN IS AND WHAT IT IS USED FOR The ingredient that makes the spray work (the active substance) is called desmopressin. Desmopressin is an antidiuretic, which reduces the amount of urine produced by the kidneys. Desmopressin nasal spray is used to: • treat and diagnose a chronic disease called DIABETES INSIPIDUS which causes extreme thirst and continuous production of large volumes of dilute urine. IMPORTANT: Not to be confused with diabetes mellitus (sugar diabetes) • treat FREQUENT URINATION DURING THE NIGHT in adults (nocturia) associated with multiple sclerosis • INVESTIGATE KIDNEY FUNCTION. 2 BEFORE YOU USE DESMOPRESSIN NASAL SPRAY DO NOT USE Desmopressin nasal spray if you: • are ALLERGIC (hypersensitive) to desmopressin or any of the other ingredients in Desmopressin nasal spray (see section 6) • DRINK unusually LARGE AMOUNTS of fluid (polydipsia) • suffer from HEART PROBLEMS, HIGH BLOOD PRESSURE or OTHER DISEASES needing TREATMENT WITH DIURETICS (water tablets) • are ELDERLY (over the age of 65 years) • suffer with ALCOHOL ABUSE. • have moderate or severe KIDNEY problems • have been told you have HYPONATRAEMIA (very low levels of sodium in your blood) • have SYNDROME OF INAPPROPRIATE ADH SECRETION (SIADH). CHECK WITH YOUR DOCTOR OR PHARMACIST BE সম্পূর্ণ নথি পড়ুন
OBJECT 1 DESMOPRESSIN NASAL SPRAY 10 MICROGRAMS/DOSE Summary of Product Characteristics Updated 09-Sep-2015 | Accord-UK Ltd 1. Name of the medicinal product Desmopressin Nasal Spray 10 micrograms/dose 2. Qualitative and quantitative composition Desmopressin acetate 0.1 mg/ml 3. Pharmaceutical form Nasal spray, solution 4. Clinical particulars 4.1 Therapeutic indications Desmopressin Nasal Spray 10 micrograms/dose is indicated for: 1) The treatment of nocturia associated with multiple sclerosis where other treatments have failed. 2) The diagnosis and treatment of vasopressin-sensitive cranial diabetes insipidus. 3) Establishing renal concentration capacity. 4.2 Posology and method of administration Each spray contains 10 micrograms desmopressin acetate. Dosage and administration _Treatment of nocturia: _For multiple sclerosis patients up to 65 years of age (with normal renal function) suffering from nocturia the dose is one or two sprays intranasally (10 to 20 micrograms) at bedtime. Not more than one dose should be used in any 24 hour period. If a dose of two sprays is required this should be as one spray in each nostril. During the treatment of nocturia the fluid intake should be limited to a minimum and only to satisfy thirst for 8 hours following administration. _Treatment of diabetes insipidus: _Dosage is individual but clinical experience has shown that the average maintenance dose in adults and children is one or two sprays (10 to 20 micrograms) once or twice daily. If a dose of two sprays is required, this should be as one spray into each nostril. _Diagnosis of diabetes insipidus: _The diagnostic test in adults and children is two sprays (20 micrograms). Failure to elaborate a concentrated urine after water deprivation, followed by the ability to do so after the administration of Desmopressin Nasal Spray 10 micrograms/dose confirms the diagnosis of cranial diabetes insipidus. Failure to concentrate after the administration suggests nephrogenic diabetes insipidus. When used for diagnostic purposes the fluid সম্পূর্ণ নথি পড়ুন