DBL PAPAVERINE HYDROCHLORIDE

দেশ: অস্ট্রেলিয়া

ভাষা: ইংরেজি

সূত্র: Department of Health (Therapeutic Goods Administration)

সক্রিয় উপাদান:

Papaverine hydrochloride

থেকে পাওয়া:

Hospira Australia Pty Ltd

শ্রেণী:

Medicine Registered

তথ্য লিফলেট

 
DBL™ Y:\PI & CMI\Approved PI & CMI\Approved CMI\Papaverine hcmi
Nov2011.doc

Page 1 

DBL™ PAPAVERINE HYDROCHLORIDE 
INJECTION 

Papaverine Hydrochloride (pa-PAV-er-een) 

CONSUMER MEDICINE INFORMATION 
_Date of Dispensing_ 
_Consumer Name _
_Pharmacist Name _
_Consumer Address _
_Pharmacist Address _

WHAT IS IN THIS LEAFLET 

This leaflet answers some 
common questions about DBL™ 
Papaverine Hydrochloride 
Injection. It does not contain all 
the available information. 
It does not take the place of 
talking to your doctor or 
pharmacist. 

All medicines have risks and 
benefits. Your doctor weighed the 
risks of you using papaverine 
against the benefits they expect it 
will have for you. 

IF YOU HAVE ANY CONCERNS ABOUT 
USING THIS MEDICINE, ASK YOUR 
DOCTOR OR PHARMACIST. 

KEEP THIS LEAFLET. 
You may need to read it again. 

WHAT DBL™

PAPAVERINE 
HYDROCHLORIDE 
INJECTION IS USED FOR 

This medicine is used to produce 
erections in impotent men. 

It belongs to a group of medicines 
called vasodilators.  

When papaverine is injected into 
the penis (called ‘intracavernosal’ 
injection) it works by increasing 
blood flow to the penis, which 
results in an erection. 

ASK YOUR DOCTOR IF YOU HAVE 
ANY QUESTIONS ABOUT WHY THIS 
PRODUCT HAS BEEN PRESCRIBED 
FOR YOU. 
Your doctor may have prescribed 
it for another reason. 

This medicine is not addictive. 

This medicine is available only 
with a doctor’s prescription. 

There is not enough information 
to recommend the use of this 
medicine for children and 
newborn babies. 

BEFORE YOU USE DBL™ 
PAPAVERINE 
HYDROCHLORIDE 
INJECTION 

_WHEN YOU MUST NOT USE IT _

DO NOT USE DBL™ PAPAVERINE 
HYDROCHLORIDE INJECTION IF YOU 
HAVE AN ALLERGY TO: 
•  any medicine containing 
papaverine  
•  any of the ingredients listed 
at the end of this leaflet. 

Symptoms of an allergic reaction 
may include shortness of brea

পণ্য বৈশিষ্ট্য

Product Information – Australia 
Version 4.0 
Page 1 
DBL™ PAPAVERINE HYDROCHLORIDE INJECTION 

NAME OF MEDICINE 
Papaverine hydrochloride  

The chemical structure is shown below.

DESCRIPTION 
Papaverine hydrochloride is the hydrochloride of an alkaloid obtained
from opium or prepared 
synthetically. It belongs to the benzylisoquinoline group of
alkaloids. The chemical name for 
papaverine hydrochloride is 6,7-dimethoxy-1-veratrylisoquinoline
hydrochloride. The molecular 
weight of papaverine hydrochloride (C
20
H
21
NO
4
,HCl) is 375.9. 

DBL™ Papaverine Hydrochloride Injection is a sterile, clear,
colourless to pale-yellow solution of 
papaverine hydrochloride in water for injection.  It is supplied in
ampoules containing 30 mg or 120 
mg of papaverine hydrochloride BP and water for injection BP/USP.
 The pH of the injection ranges 
between 3.0 and 5.0. 

PHARMACOLOGY 
The principal therapeutic action of papaverine is its relaxant effect
on smooth muscles, which leads to 
penile erection. It may induce erections by arteriolar relaxation,
increased blood flow and volume due 
to relaxation of the sinusoidal wall of the corpora cavernosa and
subsequent compression of venous 
channels between the sinusoids and the tunica albuginea.  

The spasmolytic effect of papaverine is most pronounced on the
vascular system, including coronary, 
cerebral, pulmonary and peripheral vasodilation; it also relaxes the
bronchial, gastrointestinal, biliary 
and urinary tract smooth muscles. Papaverine has also been reported
to have direct cardiac inotropic 
effects, leading to increased myocardial oxygen consumption, which can
outstrip the effect of 
increased coronary blood flow if hypotension is also present. It can
depress myocardial excitability, 
prolong the refractory period and depress myocardial conduction. In
the presence of depressed 
conduction due to other causes (eg AV block), papaverine may produce
transient ventricular 
arrhythmias. Papave