Antilice shampoo

দেশ: আর্মেনিয়া

ভাষা: ইংরেজি

সূত্র: Դեղերի և բժշկական տեխնոլոգիաների փորձագիտական կենտրոնի գործունեության Հայաստանի Հանրապետությունում

সক্রিয় উপাদান:

pyrethrins (permethrin+tetramethrin), piperonyl butoxide

থেকে পাওয়া:

Arpimed LLC

এটিসি কোড:

P03AC54

INN (আন্তর্জাতিক নাম):

pyrethrins (permethrin+tetramethrin), piperonyl butoxide

ডোজ:

1,65mg/ml+ 16,5mg/ml

ফার্মাসিউটিকাল ফর্ম:

shampoo

প্যাকেজ ইউনিট:

plastic bottle 100ml

প্রেসক্রিপশন টাইপ:

OTC

অনুমোদন অবস্থা:

Registered

অনুমোদন তারিখ:

2019-08-15

পণ্য বৈশিষ্ট্য

SUMMARY PRODUCT CHARACTERISTIC (SPC)
ANTILICE
SHAMPOO FOR EXTERNAL USE TRADE NAME
–
Antilice INTERNATIONAL NON-PROPERTY NAME
– Pyrethrins (permethrin+tetramethrin) +
Piperonyl butoxide
DOSAGE FORM
Shampoo for external use.
COMPOSITION
Each ml of Antilice shampoo contains:
_ACTIVE INGREDIENTS:_ pyrethrins (permethrin + tetramethrin) - 1.65
mg, piperonyl butoxide – 16.5 mg;
_INACTIVE INGREDIENTS:_ cocamidopropyl betaine, polyquaternium, sodium
laureth sulfate, cocamide
DEA, sodium chloride, disodium EDTA, methylparaben, citric acid, aroma
apple, color
«
apple
green
»
(E 142), water purified.
PHARMACOLOGICAL GROUP AND ATC CODE
Pediculicide; P03AC54.
PHARMACOLOGY
ANTILICE shampoo is a pediculicide combination. Following absorption
through the chitinous
exoskeleton of arthropods, pyrethrins stimulate the nervous system,
apparently by competitively
interfering with cationic conductances in the lipid layer of nerve
cells, thereby blocking nerve
impulse transmissions. Paralysis and death follow.
Piperonyl butoxide has little or no insecticidal activity but
potentates that of pyrethrins by inhibiting
the hydrolytic enzymes responsible for pyrethrin’s metabolism in
arthropods. When piperonyl
butoxide is combined with pyrethrins, the insecticidal activity of the
latter drug is increased 2-12
times.
SPECTRUM AND RESISTANCE
Pyrethrins are toxic to the parasitic arthropods _ Pediculus capitis
_(head louse), _Pediculus corporis _
(body louse), and _Phthirus pubis _(crab louse), and possibly their
nits. Resistance to pyrethrins may
develop rarely in strains of _ Pediculus corporis. _ Some lice
resistant to chlorophenothane (DDT)
have been reported to be cross-resistant to pyrethrins. Pyrethrins are
also toxic to house-flies, fleas,
chiggers, and mosquitoes.
PHARMACOKINETICS
Pyrethrins are absorbed through intact skin when applied topically.
Piperоnуl butoxide reportedly is
poorly absorbed through intact skin when applied topically.
After 24 h after treatment, the
concentration of it's components in the blood plasma i